Recombinant Mouse Ripk2 Protein, Myc/DDK-tagged

• Cat.No.: Ripk2-5522M
• Product Overview: Purified recombinant protein of mouse full-length receptor (TNFRSF)-interacting serine-threonine kinase 2 (Ripk2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the receptor-interacting protein family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain, and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of nuclear factor kappa B and inducer of apoptosis in response to various stimuli. Alternate splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 60.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 [ Mus musculus (house mouse) ]
• Official Symbol: Ripk2
• Synonyms: RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor-interacting serine/threonine-protein kinase 2; tyrosine-protein kinase RIPK2; CCK; RICK; RIP2; CARD3; CARDIAK; D4Bwg0615e; 2210420D18Rik
• Gene ID: 192656
• mRNA Refseq: NM_138952
• Protein Refseq: NP_620402
• UniProt ID: P58801