Recombinant Mouse Rit1 Protein, Myc/DDK-tagged

• Cat.No.: Rit1-5526M
• Product Overview: Purified recombinant protein of mouse full-length Ras-like without CAAX 1 (Rit1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 25.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Rit1 Ras-like without CAAX 1 [ Mus musculus (house mouse) ]
• Official Symbol: Rit1
• Synonyms: RIT1; Ras-like without CAAX 1; GTP-binding protein Rit1; ras-like without CAAX protein 1; RAS-like protein expressed in many tissues; Rit; RIBB; ROC1
• Gene ID: 19769
• mRNA Refseq: NM_009069
• Protein Refseq: NP_033095
• UniProt ID: P70426