Recombinant Mouse Ror1(Gln30-Tyr406) protein, His-tagged

• Cat.No.: Ror1-194M
• Product Overview: Recombinant Mouse Ror1(Gln30-Tyr406) protein(Q9Z139), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His
• Form: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
• Molecular Mass: The protein has a predicted MW of 43.28 kDa. Due to glycosylation, the protein migrates to 58-68 kDa based on Tris-Bis PAGE result.
• Protein Length: Gln30-Tyr406
• Endotoxin: Less than 1EU per μg by the LAL method.
• Purity: > 95% as determined by Tris-Bis PAGE
  > 95% as determined by HPLC
• Storage: -20 to -80°C for 12 months as supplied from date of receipt.
  -20 to -80°C for 3-6 months in unopened state after reconstitution.
  2-8°C for 2-7 days after reconstitution.
  Recommend to aliquot the protein into smaller quantities for optimal storage. Please avoid freeze-thaw cycles.
• Reconstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Gene Information

• Gene Name: Ror1 receptor tyrosine kinase-like orphan receptor 1 [ Mus musculus ]
• Official Symbol: Ror1
• Synonyms: ROR1; receptor tyrosine kinase-like orphan receptor 1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor related 1; neurotrophic tyrosine kinase, receptor-related 1; mRor1; Ntrkr1; 2810404D04Rik
• Gene ID: 26563
• mRNA Refseq: NM_013845
• Protein Refseq: NP_038873

Reviews

10/18/2022

Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

08/13/2022

Excellent after-sales service, solving many experimental problems.

04/12/2021

Fast and timely shipment helped me to get satisfactory experimental results in short time.

Q&As

What is the expression level of ROR1 in normal tissues.

ROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.

What are the effects of inhibiting ROR1 expression?

Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.

What biological processes is ROR1 involved in?

ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.

What diseases is ROR1 involved in?

ROR1 is involved in the study of breast, lung and ovarian cancers.