Recombinant Mouse Spdef Protein, Myc/DDK-tagged

• Cat.No.: Spdef-6088M
• Product Overview: Purified recombinant protein of mouse full-length SAM pointed domain containing ets transcription factor (Spdef), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 36.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Spdef SAM pointed domain containing ets transcription factor [ Mus musculus (house mouse) ]
• Official Symbol: Spdef
• Synonyms: SPDEF; SAM pointed domain containing ets transcription factor; SAM pointed domain-containing Ets transcription factor; prostate-specific Ets; prostate-derived Ets factor; prostate specific ets transcription factor; prostate epithelium-specific Ets transcription factor; Pse; PDEF
• Gene ID: 30051
• mRNA Refseq: NM_013891
• Protein Refseq: NP_038919
• UniProt ID: Q9WTP3