Recombinant Mouse SPHK1 Protein

• Cat.No.: SPHK1-15877M
• Product Overview: Recombinant Mouse SPHK1 full length or partial length protein was expressed.

Specification

• Source: Mammalian Cells
• Species: Mouse
• Tag: His
• Form: Liquid or lyophilized powder
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >80%
• Notes: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Storage: Store it at +4 ºC for short term. For long term storage, store it at -20 ºC～-80 ºC.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Sphk1 sphingosine kinase 1 [ Mus musculus ]
• Official Symbol: SPHK1
• Gene ID: 20698
• mRNA Refseq: NM_001172472.1
• Protein Refseq: NP_001165943.1
• UniProt ID: Q8CI15

Reviews

04/16/2023

Its seamless integration makes it possible to explore different research avenues, expanding the scope and impact of my investigations.

04/14/2020

With the manufacturer's excellent technical support and its wide range of applications, the SPHK1 protein has become an indispensable tool, aiding in my research endeavors and driving meaningful scientific discoveries.

01/03/2020

Their team of experts is readily available to address any issues that may arise, providing solutions to problems and guiding me through the experimental process.

Q&As

How does SPHK1 contribute to drug resistance in cancer?

Elevated SPHK1 levels have been associated with drug resistance in cancer cells, making it a potential target to overcome resistance mechanisms.

How does SPHK1 contribute to immune regulation?

SPHK1 regulates immune cell trafficking and function by modulating S1P levels. This is significant in autoimmune diseases and inflammatory responses.

How might the modulation of SPHK1 impact personalized medicine?

Understanding the role of SPHK1 in different diseases may contribute to the development of personalized therapeutic approaches, tailoring treatments based on individual patient characteristics and disease profiles.

How does SPHK1 influence vascular functions?

SPHK1 is involved in endothelial cell functions and angiogenesis, making it a potential target in the treatment of vascular diseases.

Can SPHK1 inhibitors be used in combination therapies?

Yes, combining SPHK1 inhibitors with other therapeutic agents is being explored to enhance treatment efficacy, especially in cancer.