Recombinant Mouse Tfdp1 Protein, Myc/DDK-tagged

• Cat.No.: Tfdp1-6377M
• Product Overview: Purified recombinant protein of mouse full-length transcription factor Dp 1 (Tfdp1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 45.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tfdp1 transcription factor Dp 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tfdp1
• Synonyms: TFDP1; transcription factor Dp 1; transcription factor Dp-1; DRTF1-polypeptide 1; E2F dimerization partner 1; cell cycle regulatory transcription factor DP1; Dp1; Drtf1
• Gene ID: 21781
• mRNA Refseq: NM_009361
• Protein Refseq: NP_033387
• UniProt ID: Q08639