Recombinant Mouse Tie1 Protein, Fc-tagged

• Cat.No.: Tie1-7355M
• Product Overview: Recombinant Murine soluble TIE-1 (Val23-Glu749) protein fused with the Fc part of human IgG1 was expressed in CHO.

Specification

• Description: Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
• Source: CHO
• Species: Mouse
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: 260 kDa
• AA Sequence: VDLTLLANLRITDPQRFFLTCVSGE AGAGRSSDPPLLLEKDDRIVRTFPP GQPLYLARNGSHQVTLRGFSKPSDL VGVFSCVGGAGARRTRVLYVHNSPG AHLFPDKVTHTVNKGDTAVLSAHVH KEKQTDVIWKNNGSYFNTLDWQEAD DGRFQLQLQNVQPPSSGIYSATYLE ASPLGSAFFRLIVRGCGAGRWGPGC VKDCPGCLHGGVCHDHDGECVCPPG FTGTRCEQACREGRFGQSCQEQCPG TAGCRGLTFCLPDPYGCSCGSGWRG SQCQEACAPDHFGADCRLQCQCQNG GTCDRFSGCVCPSGWHGVHCEKSDR IPQILSMATEVEFNIGTMPRINCAA AGNPFPVRGSMKLRKPDGTMLLSTK VIVEPDRTTAEFEVPSLTLGDSGFW ECRVSTSGGQDSRRFKVNVKVPPVP LTAPRLLAKQSRQLVVSPLVSFSGD GPISSVRLHYRPQDSTIAWSAIVVD PSENVTLMNLKPKTGYNVRVQLSRP GEGGEGGWGPSALMTTDCPEPLLQP WLESWHVEGPDRLRVSWSLPSVPLS GDGFLLRLWDGARGQERRENISFPQ ARTALLTGLTPGTHYQLDVRLYHCT LLGPASPPAHVHLPPSGPPAPRHLH AQALSDSEIQLMWQHPEAPSGPISK YIVEIQVAGGSGDPQWMDVDRPEET SIIVRGLNASTRYLFRVRASVQGLG DWSNTVEEATLGNGLQSEDPVRESR AAEEGLTRSDKTHTCPPCPAPELLG GPSVFLFPPKPKDTLMISRTPEVTC VVVDVSHEDPEVKFNWYVDGVEVHN AKTKPREEQYNSTYRVVSVLTVLHQ DWLNGKEYKCKVSNKALPAPIEKTI SKAKGQPREPQVYTLPPSREEMTKN QVSLTCLVKGFYPSDIAVEWESNGQ PENNYKTTPPMLDSDGSFFLYSKLT VDKSRWQQGNVFSCSVMHEALHNHY TQKSLSLSPGK
• Purity: > 90 % by SDS-PAGE and visualized by Silver stain
• Stability: Shelf life: one year from despatch.
• Storage: Store lyophilized at 2-8 centigrade for 6 months or at -20 centigrade long term.
  After reconstitution store the antibody undiluted at 2-8 centigrade for one month or (in aliquots) at -20 centigrade long term.
  Avoid repeated freezing and thawing.
• Storage Buffer: PBS without stabilizers
• Reconstitution: Restore in PBS or medium to a concentration not lower than 50 μg/mL. The lyophilised sTIE-1/Fc is soluble in water and most aqueous buffers.

Gene Information

• Gene Name: Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [ Mus musculus (house mouse) ]
• Official Symbol: Tie1
• Synonyms: Tie1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; TI; TIE; tie-; tie-1; D430008P04Rik; tyrosine-protein kinase receptor Tie-1; tyrosine kinase receptor 1; EC 2.7.10.1
• Gene ID: 21846
• mRNA Refseq: NM_011587
• Protein Refseq: NP_035717
• UniProt ID: Q06806