| Description : |
This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. The pancreatic islets isolated from mice lacking the encoded protein secrete less insulin in response to high glucose concentrations. Transgenic mice overexpressing the encoded protein exhibit a metabolically favorable phenotype resisting obesity and hyperglycemia on a high-fat diet. |
| Source : |
E. coli |
| Species : |
Mouse |
| Tag : |
His |
| Form : |
Freeze-dried powder |
| Molecular Mass : |
16 kDa as determined by SDS-PAGE reducing conditions. |
| Protein length : |
His24~Lys149 (Accession # Q924A4) |
| Endotoxin : |
<1.0EU per 1ug (determined by the LAL method) |
| Purity : |
>95% |
| Characteristic : |
The isoelectric point is 9.6. |
| Applications : |
SDS-PAGE; WB; ELISA; IP |
| Stability : |
The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
| Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Storage Buffer : |
Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4. |
| Reconstitution : |
Reconstitute in sterile PBS, pH7.2-pH7.4. |
