Recombinant Mouse Usp16 Protein, Myc/DDK-tagged
Cat.No. : | Usp16-6867M |
Product Overview : | Purified recombinant protein of mouse full-length ubiquitin specific peptidase 16 (Usp16), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 93.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Usp16 ubiquitin specific peptidase 16 [ Mus musculus (house mouse) ] |
Official Symbol : | Usp16 |
Synonyms : | Usp16; ubiquitin specific peptidase 16; UBP-; UBPM; 1200004E02Rik; 2810483I07Rik; 6330514E22Rik; ubiquitin carboxyl-terminal hydrolase 16; deubiquitinating enzyme 16; ubiquitin specific protease 16; ubiquitin thioesterase 16; ubiquitin thiolesterase 16; ubiquitin-specific-processing protease 16; EC 3.4.19.12 |
Gene ID : | 74112 |
mRNA Refseq : | NM_024258 |
Protein Refseq : | NP_077220 |
UniProt ID : | Q99LG0 |
Products Types
◆ Recombinant Protein | ||
USP16-6127R | Recombinant Rat USP16 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP16-362H | Recombinant Human USP16 Protein, His-tagged | +Inquiry |
USP16-4936R | Recombinant Rhesus Macaque USP16 Protein, His (Fc)-Avi-tagged | +Inquiry |
USP16-1219H | Recombinant Human USP16 Protein (G2-L823), Tag Free | +Inquiry |
USP16-1218H | Recombinant Human USP16 Protein (G2-L823), His tagged | +Inquiry |
◆ Lysates | ||
USP16-470HCL | Recombinant Human USP16 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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