Recombinant Mouse Vps33b Protein, Myc/DDK-tagged

• Cat.No.: Vps33b-6938M
• Product Overview: Purified recombinant protein of Mouse vacuolar protein sorting 33B (Vps33b), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages. Proposed to be involved in endosomal maturation implicating in part VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependentrecycling pathway and in the maintenance of the apical-basolateral polarity. Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 70.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Vps33b vacuolar protein sorting 33B [ Mus musculus (house mouse) ]
• Official Symbol: Vps33b
• Synonyms: VPS33B; vacuolar protein sorting 33B (yeast); vacuolar protein sorting-associated protein 33B; MGC36556
• Gene ID: 233405
• mRNA Refseq: NM_178070
• Protein Refseq: NP_835171
• UniProt ID: P59016