Recombinant Pig CALR Protein (18-417 aa), His-tagged CALR-2130P

Recombinant Pig CALR Protein (18-417 aa), His-tagged

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Cat.No. : CALR-2130P Optional Service: Optional requirements on this protein
Product Overview : Recombinant Pig CALR Protein (18-417 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Tags & Cell Markers. Protein Description: Full Length of Mature Protein.
Description : Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.
Source : Yeast
Species : Pig
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 48.6 kDa
Protein length : 18-417 aa
AA Sequence : EPTIYFKEQF LDGDGWTDRW IESKHKPDFG RFVLSSGKFY GDQEKDKGLQ TSQDARFYAL SARFEPFSNK GQTLVVQFTV KHEQNIDCGG GYVKLFPDGL DQTDMHGDSE YNIMFGPDIC GPGTKKVHVI FNYKGKNVLI NKDIRCKDDE FTHLYTLIVR PDNTYEVKID NSQVESGSLE DDWDFLPPKK IKDPDAVKPE DWDERAKIDD PTDSKPEDWD KPEHIPDPDA KKPEDWDEEM DGEWEPPVIQ NPEYKGEWKP RQIDNPDYKG TWIHPEIDNP EYSPDSNIYA YENFAVLGLD LWQVKSGTIF DNFLITNDEA YAEEFGNETW GVTKAAEKQM KDKQDEEQRL KEEEEEKKRK EEEEVDKEDE EDKDEDEEEE DEKEEEEEED AAAGQAKDEL
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : CALR calreticulin [ Sus scrofa ]
Official Symbol : CALR
Synonyms : CALR; calreticulin;
Gene ID : 100381266
mRNA Refseq : NM_001174133
Protein Refseq : NP_001167604
UniProt ID : P28491
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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