Recombinant Pig CCL5 protein, His & T7-tagged

• Cat.No.: CCL5-775P
• Product Overview: Recombinant Pig CCL5 aa. (Ser24~Ser91 (Accession # Q2EN89)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Source: E. coli
• Species: Pig
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 11.6kDa
• Protein length: Ser24~Ser91 (Accession # Q2EN89)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH 7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: CCL5 C-C motif chemokine ligand 5 [ Sus scrofa (pig) ]
• Official Symbol: CCL5
• Synonyms: SCYA5; RANTES; SIS-delta; T-cell-specific protein RANTES; small-inducible cytokine A5; C-C motif chemokine 5; chemokine (C-C motif) ligand 5
• Gene ID: 396613
• mRNA Refseq: NM_001129946.1
• Protein Refseq: NP_001123418.1
• UniProt ID: Q2EN89

Reviews

08/17/2021

This specificity enables precise quantification and characterization of CCL5 and its interactions with other molecules or proteins of interest.

06/23/2019

Its exceptional performance, coupled with its ability to generate clear and precise protein bands, make it an indispensable tool in achieving accurate and reliable results.

06/20/2016

The CCL5 protein exhibits a high degree of specificity in various assays, ensuring accurate and reliable results.

Q&As

What are the potential clinical applications of CCL5 inhibitors?

CCL5 inhibitors may be used to control inflammation in diseases like rheumatoid arthritis or as an adjuvant in cancer therapy.

Can CCL5 be used to stimulate the immune system in cancer treatment?

CCL5-based immunotherapies are being explored to enhance the immune response against cancer cells.

Can CCL5 be used as a diagnostic marker for diseases?

It can serve as a biomarker for some diseases, but it is usually used in conjunction with other markers for more accurate diagnostics.

What are the clinical implications of elevated CCL5 levels?

Elevated CCL5 levels are associated with inflammation and may be indicative of certain diseases such as rheumatoid arthritis or HIV infection.

Are there any CCL5-targeted therapies in development?

Yes, there are ongoing efforts to develop therapies that modulate CCL5 activity, particularly in diseases involving inflammation.