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Recombinant Rabbit S100A12 protein, His & T7-tagged

Cat.No. : S100A12-1480R
Product Overview : Recombinant Rabbit S100A12 aa. (Thr2~Glu92 (Accession # O77791)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Source : E. coli
Species : Rabbit
Tag : His&T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 14.2kDa.
Protein length : Thr2~Glu92
Endotoxin : <1.0EU per 1µg (determined by the LAL method).
Purity : >95%
Characteristic : The isoelectric point is 5.4.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : S100A12 S100 calcium binding protein A12 [ Oryctolagus cuniculus (rabbit) ]
Official Symbol : S100A12
Synonyms : protein S100-A12; calgranulin C
Gene ID : 100008703
mRNA Refseq : XM_002715516.3
Protein Refseq : XP_002715562.2
UniProt ID : O77791

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
09/30/2022

    Precise protein quantification, fundamental for data accuracy in our experiments.

    03/11/2020

      Timely antibody validation, a valuable asset for our laboratory.

      02/26/2019

        Exceptional protein expression optimization support, greatly enhances our research.

        Q&As (7)

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        What are the mechanisms by which S100A12 modulates the expression of pro-inflammatory cytokines? 11/30/2022

        S100A12 regulates the production of pro-inflammatory cytokines, impacting the extent and severity of inflammation.

        What role does S100A12 play in the pathogenesis of inflammatory diseases like rheumatoid arthritis? 03/16/2022

        S100A12 is implicated in inflammatory diseases like rheumatoid arthritis, contributing to joint inflammation and damage.

        What is the impact of S100A12 on vascular inflammation and the development of atherosclerosis? 02/23/2022

        S100A12 contributes to vascular inflammation, potentially leading to the development of atherosclerosis.

        How does S100A12 contribute to the innate immune response, particularly in bacterial infections? 04/25/2021

        S100A12 plays a role in the innate immune response against bacterial infections, enhancing pathogen detection and response.

        How do alterations in S100A12 expression or function affect chronic inflammatory conditions and autoimmune diseases? 06/20/2020

        Changes in S100A12 expression can exacerbate chronic inflammatory and autoimmune diseases, affecting disease progression and symptoms.

        How does S100A12 influence calcium signaling and cellular activation in immune cells? 02/20/2020

        S100A12 influences calcium signaling in immune cells, affecting their activation and function.

        How does S100A12 (S100 Calcium Binding Protein A12) interact with receptors on immune cells to modulate inflammation? 01/10/2018

        S100A12 binds to receptors on immune cells, triggering inflammatory responses and modulating immune activity.

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