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Recombinant Rat Csf2 Protein, His-tagged

Cat.No. : Csf2-1285R
Product Overview : Recombinant Rat Csf2 Protein (Ala18-Lys144) with N-His tag was expressed in E. coli.
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Description : Enables cytokine activity. Involved in several processes, including cellular response to lipopolysaccharide; macrophage activation; and response to silicon dioxide. Located in extracellular space. Used to study Parkinsonism and myocardial infarction. Biomarker of abdominal aortic aneurysm; interstitial cystitis; and lung disease (multiple). Human ortholog(s) of this gene implicated in acute myeloid leukemia; juvenile myelomonocytic leukemia; neutropenia; pulmonary alveolar proteinosis; and visceral leishmaniasis. Orthologous to human CSF2 (colony stimulating factor 2).
Source : E. coli
Species : Rat
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 44.5 kDa
Accurate Molecular Mass: 45 kDa
Protein length : Ala18-Lys144
Purity : > 95%
Applications : Cell culture; Activity Assays.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : Csf2 colony stimulating factor 2 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Csf2
Synonyms : Csf2; colony stimulating factor 2; Gmcsf; Gm-csf; granulocyte-macrophage colony-stimulating factor; CSF; colony stimulating factor 2 (granulocyte-macrophage); colony-stimulating factor
Gene ID : 116630
mRNA Refseq : NM_053852
Protein Refseq : NP_446304
UniProt ID : P48750

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How conserved is the sequence of CSF2 among different species? 05/15/2021

The sequence of CSF2 is moderately conserved across different species.

What is the typical length of CSF2? 01/30/2021

The length of CSF2 protein varies but is typically around 144 amino acids.

What is the main biological function of CSF2? 05/01/2019

The primary function of CSF2 is to regulate the production and differentiation of white blood cells.

In what tissues or cells is CSF2 commonly expressed? 02/03/2019

CSF2 is often expressed in immune cells, specifically in macrophages, T cells, and endothelial cells.

What does CSF2 stand for? 07/10/2018

CSF2 stands for Colony Stimulating Factor 2.

Is CSF2 associated with any specific diseases or conditions? 03/17/2018

CSF2 dysregulation has been linked to autoimmune diseases and inflammatory disorders.

Which cellular functions are associated with CSF2? 02/20/2017

CSF2 is involved in the stimulation of stem cells to produce granulocytes and monocytes.

Customer Reviews (3)

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Reviews
01/15/2022

    The product's adherence to regulatory standards aligned with our lab's commitment to responsible and transparent research.

    07/27/2021

      The manufacturer's commitment to meeting regulatory requirements demonstrated its dedication to ethical research practices.

      05/19/2019

        Compliance with industry standards minimized potential roadblocks in securing approvals for our experiments.

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