Recombinant Rat Il1rn Protein, His-tagged Il1rn-2299R

Recombinant Rat Il1rn Protein, His-tagged

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Cat.No. : Il1rn-2299R Optional Service: Optional requirements on this protein
Product Overview : Recombinant Rat Il1rn Protein (His27-Gln178) with a N-His tag was expressed in E. coli.
Description : Enables interleukin-1 receptor binding activity. Involved in several processes, including cellular response to norepinephrine stimulus; chronic inflammatory response to antigenic stimulus; and fever generation. Located in extracellular space. Used to study adult respiratory distress syndrome; anti-basement membrane glomerulonephritis; hypertension; silicosis; and transient cerebral ischemia. Biomarker of encephalitis and pneumonia. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); eye disease (multiple); kidney failure (multiple); lung disease (multiple); and vascular disease (multiple). Orthologous to human IL1RN (interleukin 1 receptor antagonist).
Source : E. coli
Species : Rat
Tag : N-His
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 20.42 kDa
Accurate Molecular Mass: 21 kDa
Protein length : His27-Gln178
Endotoxin : <1.0 EU per 1µg (determined by the LAL method).
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
SDS-PAGE :

Gene Name : Il1rn interleukin 1 receptor antagonist [ Rattus norvegicus (Norway rat) ]
Official Symbol : Il1rn
Synonyms : Il1rn; interleukin 1 receptor antagonist; IL-1ra; interleukin-1 receptor antagonist protein
IL-1RN
IL1 inhibitor
IRAP
Gene ID : 60582
mRNA Refseq : NM_022194
Protein Refseq : NP_071530
UniProt ID : P25086
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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