Recombinant Rat interleukin 4 Protein, His&Flag tagged

• Cat.No.: Il4-156R
• Product Overview: Recombinant rat IL-4 protein (P20096) (Cys 25-Ser 147) with both His, Flag tag at the C-terminus was expressed in HEK293.

Specification

• Species: Rat
• Source: HEK293
• Tag: Flag&His
• Protein Length: 25-147aa
• Description: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
• Tag: C-His&Flag
• Molecular Mass: 15.1 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: Il4 interleukin 4 [ Rattus norvegicus ]
• Official Symbol: Il4
• Synonyms: IL4; interleukin 4; interleukin-4; IL-4; BSF-1; B-cell growth factor 1; B-cell stimulatory factor 1; lymphocyte stimulatory factor 1; B-cell IGG differentiation factor; Il4e12
• Gene ID: 287287
• mRNA Refseq: NM_201270
• Protein Refseq: NP_958427
• UniProt ID: P20096