Recombinant Rat KNG1 Protein (390-639 aa), His-tagged
Cat.No. : | KNG1-1435R |
Product Overview : | Recombinant Rat KNG1 Protein (390-639 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Protein Description: Partial. |
- Specification
- Gene Information
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Description : | 1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting. |
Source : | Yeast |
Species : | Rat |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 29.8 kDa |
Protein length : | 390-639 aa |
AA Sequence : | APRVKKPKESTTVSPSYIARVQEER DPGNEQGPIHGHGWLHAKQIKNKNH QGHKHGHGIGHGHQKPHGLGHGHQL KLDDLKQQREDGYDHRHPVGHGHGQ RHGHGHGHGHGRDKHTNKDKNNVKH TDQRRAPLTSSSEDNTTSTQIQGRT EGFTLNPPLAQPAVISRGFQDSGFT EGVIATTSPYDTETHDDLIPDIHVQ PDSLSFKLISDFPEATSHKCPGRPW KPVSRKDPTIETTEFSDFDLLDALS |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Kng1 kininogen 1 [ Rattus norvegicus ] |
Official Symbol : | KNG1 |
Synonyms : | KNG1; kininogen 1; Kng; Tkg; Kngk; Kngt; Map1; TKG6; KINKG; KINKH; Kngt1; KINT1G; Kng_v1; Kng1_v1; MGC93589; |
Gene ID : | 24903 |
mRNA Refseq : | NM_012696 |
Protein Refseq : | NP_036828 |
UniProt ID : | P08934 |
Products Types
◆ Recombinant Protein | ||
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KNG1-687H | Recombinant Human KNG1 Protein, MYC/DDK-tagged | +Inquiry |
Kng1-3300M | Active Recombinant Mouse Kng1 protein(Glu21-Ser480), His-tagged | +Inquiry |
Kng1-4893M | Recombinant Mouse Kng1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
KNG1-1844H | Native Human Kininogen 1 | +Inquiry |
KNG1-18H | Native Human Kininogen, LMW | +Inquiry |
KNG1-29338TH | Native Human KNG1 | +Inquiry |
◆ Lysates | ||
KNG1-2284HCL | Recombinant Human KNG1 cell lysate | +Inquiry |
KNG1-2276MCL | Recombinant Mouse KNG1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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