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Recombinant Rat Pfkm protein, His & T7-tagged

Cat.No. : Pfkm-8011R
Product Overview : Recombinant Rat Pfkm aa. (Thr2~His390 (Accession # P47858)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : Phosphofructokinase isozyme A; may regulate glycolytic flux and influence insulin secretion.
Source : E. coli
Species : Rat
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 46.3kDa
Protein length : Thr2~His390 (Accession # P47858)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.1.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Pfkm phosphofructokinase, muscle [ Rattus norvegicus (Norway rat) ]
Official Symbol : Pfkm
Synonyms : Pfkm; phosphofructokinase, muscle; PFK-A; Pfk-M; ATP-PFK; ATP-dependent 6-phosphofructokinase, muscle type; 6-phosphofructokinase type A; 6-phosphofructokinase, muscle type; phosphofructo-1-kinase isozyme A; phosphofructokinase 1; phosphofructokinase-A; phosphofructokinase-M; phosphohexokinase
Gene ID : 65152
mRNA Refseq : NM_031715.1
Protein Refseq : NP_113903.1
UniProt ID : P47858

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any known drug interactions involving PFKM-related therapies? 06/27/2019

Drug interactions involving PFKM-related therapies have not been extensively studied, but caution should be exercised in combination with other medications.

Can PFKM mutations be inherited? 11/29/2018

Yes, PFKM deficiency is an autosomal recessive disorder, meaning it can be passed on from both parents.

How can PFKM protein be targeted for therapeutic interventions? 09/17/2018

Targeting PFKM with small molecule inhibitors or gene therapies is being explored as potential treatment strategies.

Can PFKM levels be used as a biomarker for certain diseases? 01/11/2018

PFKM levels have been studied as potential biomarkers for cancer and metabolic disorders, but more research is needed for clinical application.

Are there any known associations between PFKM and cardiovascular diseases? 01/17/2016

Research suggests that PFKM may play a role in cardiac energy metabolism and could be implicated in cardiovascular diseases.

Customer Reviews (3)

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Reviews
09/25/2022

    As a researcher, utilizing PFKM protein in trials offers numerous advantages that contribute to the successful completion of experiments and the acquisition of valuable data.

    03/14/2022

      manufacturers offer customization options, such as alternative conjugation methods or tailored formulations, allowing researchers to optimize PFKM protein to their specific experimental needs.

      06/04/2021

        This ensures the consistency and reproducibility of experimental results, promoting confidence in the obtained data.

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