Recombinant Rat S100a8 Protein, His-tagged

• Cat.No.: S100a8-1361R
• Product Overview: Recombinant Rat S100a8 Protein (2-89aa) was expressed in E. coli with N-terminal His tag.

Specification

• Source: E. coli
• Species: Rat
• Tag: His
• Form: Tris-based buffer, 50% glycerol.
• Molecular Mass: 14.1 kDa
• AA Sequence: ATELEKALSNVIEVYHNYSGIKGNH HALYRDDFRKMVTTECPQFVQNKNT ESLFKELDVNSDNAINFEEF
  LVLVIRVGVAAHKDSHKE
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: The shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Protein length: 2-89

Gene Information

• Gene Name: S100a8 S100 calcium binding protein A8 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: S100a8
• Synonyms: Mrp8
• Gene ID: 116547
• mRNA Refseq: NM_053822.2
• Protein Refseq: NP_446274.2
• UniProt ID: P50115

Reviews

02/01/2022

Dependable protein quantification, ensures experimental accuracy.

10/29/2020

Consistent western blot results, a lab essential.

03/12/2020

Expert protein engineering support, essential for our projects.

Q&As

How do alterations in S100A8 expression impact cellular stress responses and aging?

Changes in S100A8 expression impact cellular stress responses, with implications for aging and age-related diseases.

How does S100A8 contribute to the pathogenesis of cancer, especially in terms of tumor growth and metastasis?

S100A8 contributes to cancer development, influencing tumor cell proliferation and metastatic potential.

What is the impact of S100A8 on wound healing and tissue repair mechanisms?

S100A8 is involved in wound healing, affecting tissue repair and regeneration.

How does S100A8 interact with calcium ions and what are the implications for inflammatory processes?

S100A8 binds calcium ions, modulating inflammatory processes and cytokine production.

How does S100A8 influence the development and progression of cardiovascular diseases?

S100A8 affects cardiovascular disease development, impacting inflammation and vascular integrity.

What role does S100A8 play in the immune response, particularly in autoimmune diseases?

S100A8 plays a significant role in the immune response, impacting the pathogenesis of autoimmune diseases.

What are the effects of S100A8 on skin homeostasis and the development of skin disorders?

S100A8 influences skin health, playing a role in maintaining skin barrier function and in skin disorders.