Recombinant Rat Tnni3 protein, His-tagged

• Cat.No.: Tnni3-179R
• Product Overview: Recombinant Rat Tnni3 fused with His tag was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: His
• Description: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.
• Form: Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
• Molecular Mass: 25.7 kDa
• Purity: Greater than 95%
• Storage: Store at +4 centigrade for up to 1 month, or aliquot and store at -80 centigrade for up to 12 months. Avoid repeat freeze-thaw cycles.

Gene Information

• Gene Name: Tnni3 troponin I type 3 (cardiac) [ Rattus norvegicus ]
• Official Symbol: Tnni3
• Synonyms: TNNI3; troponin I type 3 (cardiac); troponin I, cardiac muscle; cardiac troponin I; troponin 1, type 3; TnI; cTNI
• Gene ID: 29248
• mRNA Refseq: NM_017144
• Protein Refseq: NP_058840
• UniProt ID: P23693
• Chromosome Location: 1q12
• Pathway: Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem
• Function: actin binding; actin binding; calcium channel inhibitor activity; calcium channel inhibitor activity; calcium-dependent protein binding; calcium-dependent protein binding; protein domain specific binding; protein domain specific binding; protein kinase binding; protein kinase binding; troponin C binding; troponin C binding; troponin T binding; troponin T binding