Recombinant Rhesus Monkey VTCN1 Protein, hIgG4-tagged

Cat.No. : VTCN1-1518R
Product Overview : Recombinant Rhesus monkey VTCN1 Protein (XP_001103715 ( aa.25-259)) was expressed in human HEK293 cells with hIgG4 tag.
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Description : B7H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. B7H4 is highly expressed on a number of tumor cells, including breast cancer.
Source : HEK293
Species : Rhesus monkey
Tag : hIgG4
Form : PBS, pH7.4.
Purity : > 95 %
Applications : WB; ELISA; Immunogen
Storage : -80 centigrade, Avoid freeze/thaw cycle.
Concentration : 1 mg/mL
Protein length : 25-259
Gene Name : VTCN1 V-set domain containing T-cell activation inhibitor 1 [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : VTCN1
Synonyms : VTCN1; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; B7 family member; H4; B7 superfamily member 1; B7 H4; B7H4; B7S1; B7X; FLJ22418; B7 family member; H4; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; immune costimulatory protein B7-H4; B7-H4; B7h.5; VCTN1; PRO1291; RP11-229A19.4;
Gene ID : 714123
mRNA Refseq : XM_001103715.3
Protein Refseq : XP_001103715

Not For Human Consumption!

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