Recombinant SARS-CoV-2 Spike S (Q14-Q1208) Protein, Fc-tagged

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Recombinant SARS-CoV-2 Spike S (Q14-Q1208) Protein, Fc-tagged

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Cat.No. : M-093S
Product Overview : Recombinant protein of severe acute respiratory syndrome coronavirus 2 Spike S (S1+S2, Q14-Q1208), with a rabbit IgG Fc tag was expressed in human cells.
Description : The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. The SARS-CoV-2 spike (S) protein is composed of two subunits; the S1 subunit contains a receptor-binding domain that engages with the host cell receptor angiotensin-converting enzyme 2 and the S2 subunit mediates fusion between the viral and host cell membranes. The S RBD protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity, during infection with SARS-CoV-2 (2019-nCoV) as in recent COVID-19 outbreak.
Source : Human cells
Species : SARS-CoV-2
Tag : Fc
Molecular Mass : 158 kDa
Endotoxin : Endotoxin level is < 0.1 ng/μg of protein (< 1 EU /μg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only!
Storage Buffer : Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives
SDS-PAGE :

Gene Name : M membrane glycoprotein [ Severe acute respiratory syndrome coronavirus 2 ]
Official Symbol : M
Synonyms : M; membrane glycoprotein; membrane glycoprotein; ORF5; structural protein
Gene ID : 43740571
mRNA Refseq : MN908947
Protein Refseq : YP_009724390
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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