Recombinant Sheep PTGS2 Protein PTGS2-010S

Recombinant Sheep PTGS2 Protein

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Recombinant Sheep PTGS2 Protein

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Cat.No. : PTGS2-010S
Product Overview : Recombinant Sheep PTGS2 protein (24-599) without tag was expressed in Sf21 cells
Description : Cyclooxygenase (COX)-1 and -2, also called prostaglandin endoperoxide H synthases-1 and -2 (PGHS-1 and -2) are key regulatory enzymes in the PG biosynthetic pathway. COX enzymes catalyze the committed step in the conversion of arachidonic acid to PGH2. These enyzmes are the major targets for NSAIDs that are used to reduce pain, inflammation, and fever.
Source : Insect Cells
Species : Sheep
Bio-activity : >20,000 U/mg (minimum)
Molecular Mass : 70 kDa
Protein length : 24-599
Purity : ≥80% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to consume 1 nmol of oxygen per minute 37 centigrade in 100 mM Tris, pH 8.0, containing 100 µM arachidonate, 5 mM EDTA, 2 mM phenol, and 1 µM hematin.
Stability : ≥ 6 months
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
SDS-PAGE Analysis of PTGS2 :

Lane 1: MW Markers
Lane 2: COX-2 (2 µg)
Lane 3: COX-2 (5 µg)

Gene Name : PTGS2 prostaglandin-endoperoxide synthase 2 [ Ovis aries (sheep) ]
Official Symbol : PTGS2
Synonyms : PTGS2; prostaglandin-endoperoxide synthase 2; PGHS-2; prostaglandin G/H synthase 2; COX-2; PGH synthase 2; PHS II; cyclooxygenase, prostaglandin endoperoxide H synthase-2; cyclooxygenase-2; prostaglandin H synthase-2; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); EC 1.14.99.1
Gene ID : 443460
mRNA Refseq : NM_001009432
Protein Refseq : NP_001009432
UniProt ID : P79208

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