Active Recombinant Sheep PTGS2 Protein

• Cat.No.: PTGS2-010S
• Product Overview: Recombinant Sheep PTGS2 protein (24-599) without tag was expressed in Sf21 cells

Specification

• Description: Cyclooxygenase (COX)-1 and -2, also called prostaglandin endoperoxide H synthases-1 and -2 (PGHS-1 and -2) are key regulatory enzymes in the PG biosynthetic pathway. COX enzymes catalyze the committed step in the conversion of arachidonic acid to PGH2. These enyzmes are the major targets for NSAIDs that are used to reduce pain, inflammation, and fever.
• Source: Insect Cells
• Species: Sheep
• Bio-activity: >20,000 U/mg (minimum)
• Molecular Mass: 70 kDa
• Protein length: 24-599
• Purity: ≥80% estimated by SDS-PAGE
• Unit Definition: One unit is defined as the amount of enzyme required to consume 1 nmol of oxygen per minute 37 centigrade in 100 mM Tris, pH 8.0, containing 100 µM arachidonate, 5 mM EDTA, 2 mM phenol, and 1 µM hematin.
• Stability: ≥ 6 months
• Storage: -80 centigrade
• Shipping: Dry ice in continental US, may vary elsewhere.

Gene Information

• Gene Name: PTGS2 prostaglandin-endoperoxide synthase 2 [ Ovis aries (sheep) ]
• Official Symbol: PTGS2
• Synonyms: PTGS2; prostaglandin-endoperoxide synthase 2; PGHS-2; prostaglandin G/H synthase 2; COX-2; PGH synthase 2; PHS II; cyclooxygenase, prostaglandin endoperoxide H synthase-2; cyclooxygenase-2; prostaglandin H synthase-2; prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); EC 1.14.99.1
• Gene ID: 443460
• mRNA Refseq: NM_001009432
• Protein Refseq: NP_001009432
• UniProt ID: P79208