ROR1-coupled magnetic beads

• Cat.No.: ROR1-014M
• Product Overview: The biotinylated ROR1 protein was conjugated to streptavidin magnetic beads. This pre-coupled magnetic bead product can capture the anti-ROR1 antibody from various assay systems. The beads are in uniform size, narrow size distribution with large surface area and unique surface coating, which can help you get the best performance and highly reproducible results. This ROR1 coupled magnetic beads will bring great convenience with minimum non-specific binding and developed protocols. This ready-to-use product could greatly save your time and hassle.

Specification

• Species: Human
• Beads Size: 2mg
• Particle size: 2 μm
• Beads Surface: hydrophilic
• Coupled amount of protein: >300 pmol /mg Beads
• Capacity: > 200 pmol antibody/ mg beads
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, 0.05% Tween-20, pH7.4, with 10% trehalose
• Reconstitution: 2 mL ultrapure water (1mg beads/mL)
• Application: This product is intended for immunocapture, biopanning and flow cytometry.
• Storage: Upon receipt, please store the Beads at -20ºC for 1 year in lyophilized state. Once the Beads reconstitution, please use it immediately. Do not to freeze thaw the Beads after reconstitution.
• Assay Principles: The conjugation was achieved by means of the binding between streptavidin and biotin. Streptavidin (SA) has an extraordinarily high affinity for biotin with a dissociation constant (Kd) on the order of 10-14 mol/L. Thus, the binding of streptavidin and biotin is irreversible. Our ROR1 pre-coupled beads could capture anything binding to ROR1, and make the following testing easy, such as immunocapture, biopanning and flow cytometry.
• Application Method: a) Reconstitute the Beads following the COA. Wash and re-suspended the beads to a certain concentration by adding your dilution buffer.
  b) Add the prepared beads to your samples.
  c) Beads can be separated from your samples afterwards using a magnetic plate.

Reviews

10/18/2022

Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

08/13/2022

Excellent after-sales service, solving many experimental problems.

04/12/2021

Fast and timely shipment helped me to get satisfactory experimental results in short time.

Q&As

What is the expression level of ROR1 in normal tissues.

ROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.

What are the effects of inhibiting ROR1 expression?

Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.

What biological processes is ROR1 involved in?

ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.

What diseases is ROR1 involved in?

ROR1 is involved in the study of breast, lung and ovarian cancers.