CD63 Protein, CD63 molecule

CD63

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CD63

Official Full Name CD63 molecule
Background The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Synonyms CD63; CD63 molecule; MLA1; ME491; LAMP-3; OMA81H; TSPAN30; CD63 antigen; tspan-30; granulophysin; tetraspanin-30; melanoma-associated antigen MLA1; CD63 antigen (melanoma 1 antigen); melanoma-associated antigen ME491; ocular melanoma-associated antigen; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3;
    • Species :
    • Cynomolgus
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • Fc
    • GST
    • His
    • SUMOstar
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD63-2512H Recombinant Human CD63 Protein (103-203 aa), His-sumostar-tagged Yeast His/SUMOstar
    Mouse CD63-396M Recombinant Mouse CD63 Protein (103-203 aa), GST-tagged E.coli GST
    Human CD63-0840H Recombinant Human CD63 Protein Wheat Germ N/A
    Human CD63-1913HCL Recombinant Human CD63 cell lysate Human Cell N/A
    Human CD63-3112H Recombinant Human CD63 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CD63-3890H Recombinant Human CD63, His tagged Human Cell His
    Human CD63-6837H Recombinant Human CD63 protein, His & GST-tagged E.coli His/GST
    Mouse CD63-3102M Recombinant Mouse CD63 Protein Mammalian Cell His
    Mouse Cd63-878M Recombinant Mouse Cd63 Protein, Fc-tagged HEK293 Fc
    Mouse Cd63-879M Recombinant Mouse Cd63 Protein HEK293 N/A
    Rat CD63-001RCL Recombinant Rat CD63 cell lysate Human Cell N/A
    Rat CD63-1261R Recombinant Rat CD63 Protein Mammalian Cell His
    Rat Cd63-30R Recombinant Rat Cd63, His tagged Human Cell His
    Rat Cd63-546R Recombinant Rat Cd63, Fc-tagged Human Cell Fc
    Cynomolgus CD63-101C Recombinant Cynomolgus CD63 Protein, His-tagged HEK293 His
    Cynomolgus Monkey CD63-814CCL Recombinant Cynomolgus CD63 cell lysate Human Cell N/A
    Rhesus Macaque CD63-747R Recombinant Rhesus monkey CD63 Protein, His-tagged Mammalian Cell His
    Zebrafish CD63-9948Z Recombinant Zebrafish CD63 Mammalian Cell His
    Pig CD63-1553SCL Recombinant Sus scrofa (Pig) CD63 cell lysate Human Cell N/A
    Pig CD63-570P Recombinant Pig CD63 Protein, Fc-tagged HEK293 Fc

    CD63 involved in several pathways and played different roles in them. We selected most pathways CD63 participated on our site, such as Lysosome, Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Lysosome TCEAL4; AP4S1; CLN5; SCARB2; CTSA; GNPTAB; ATP6V0A2B; ATP6V0D1; NPC2; CTNS
    Proteoglycans in cancer ESR1; WNT5A; CBL; PIK3CD; MDM2; CDC42; CBLB; Ctsl; MAPK12; RPS6KB1

    CD63 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD63 itself. We selected most functions CD63 had, and list some proteins which have the same functions with CD63. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CLEC18A; MTF1; TRIP4; KRT2; ZBTB44; SDCCAG8; ANP32A; CPT1B; VPS33B; DIP2A

    CD63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD63 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD63.

    env; TIMP1; LMP1; ITGB1; SRC; Ptpra; Enam; Ambn; q6krg0_bacan; Amelx

    Antoine, F; Girard, D; et al. Curcumin increases gelatinase activity in human neutrophils by a p38 mitogen-activated protein kinase (MAPK)-independent mechanism. JOURNAL OF IMMUNOTOXICOLOGY 12:188-193(2015).
    Scadding, GW; Eifan, A; et al. Local and systemic effects of cat allergen nasal provocation. CLINICAL AND EXPERIMENTAL ALLERGY 45:613-623(2015).

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