|Official Full Name||CD63 molecule|
|Background||The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]|
|Synonyms||CD63; CD63 molecule; MLA1; ME491; LAMP-3; OMA81H; TSPAN30; CD63 antigen; tspan-30; granulophysin; tetraspanin-30; melanoma-associated antigen MLA1; CD63 antigen (melanoma 1 antigen); melanoma-associated antigen ME491; ocular melanoma-associated antigen; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CD63 involved in several pathways and played different roles in them. We selected most pathways CD63 participated on our site, such as Lysosome, Proteoglycans in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Lysosome||TCEAL4; AP4S1; CLN5; SCARB2; CTSA; GNPTAB; ATP6V0A2B; ATP6V0D1; NPC2; CTNS|
|Proteoglycans in cancer||ESR1; WNT5A; CBL; PIK3CD; MDM2; CDC42; CBLB; Ctsl; MAPK12; RPS6KB1|
CD63 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD63 itself. We selected most functions CD63 had, and list some proteins which have the same functions with CD63. You can find most of the proteins on our site.
|protein binding||CLEC18A; MTF1; TRIP4; KRT2; ZBTB44; SDCCAG8; ANP32A; CPT1B; VPS33B; DIP2A|
CD63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD63 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD63.
env; TIMP1; LMP1; ITGB1; SRC; Ptpra; Enam; Ambn; q6krg0_bacan; Amelx