Recombinant Full Length Human CD63 Protein, C-Flag-tagged

• Cat.No.: CD63-180HFL
• Product Overview: Recombinant Full Length Human CD63 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 25.5 kDa
• AA Sequence: MAVEGGMKCVKFLLYVLLLAFCACA VGLIAVGVGAQLVLSQTIIQGATPG SLLPVVIIAVGVFLFLVAFV GCCGACKENYCLMITFAIFLSLIML VEVAAAIAGYVFRDKVMSEFNNNFR QQMENYPKNNHTASILDRMQ ADFKCCGAANYTDWEKIPSMSKNRV PDSCCINVTVGCGINFNEKAIHKEG CVEKIGGWLRKNVLVVAAAA
  LGIAFVEVLGIVFACCLVKSIRSGY EVMTRTRPLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Lysosome

Gene Information

• Gene Name: CD63 CD63 molecule [ Homo sapiens (human) ]
• Official Symbol: CD63
• Synonyms: MLA1; ME491; LAMP-3; OMA81H; TSPAN30
• Gene ID: 967
• mRNA Refseq: NM_001780.6
• Protein Refseq: NP_001771.1
• MIM: 155740
• UniProt ID: P08962