Cd80 Protein, CD80 antigen


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Official Full Name CD80 antigen
Background Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode of action is by bindin
Synonyms CD80; CD80 antigen; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17; T-lymphocyte activation antigen CD80; B7 protein; activation B7-1 antigen; B7; BB1; LAB7; CD28LG; CD28LG1; OTTHUMP00000215214; OTTHUMP00000215215; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Cynomolgus/Rhesus macaque
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • NS0
    • NSO
    • Wheat Germ
    • Tag :
    • Avi
    • Fc
    • His
    • DDK
    • Fc Chimera
    • GST
    • hIgG1
    • hIgG4
    • Flag
    • StrepII
    • human
    • IgG1
    • Mouse
    • IgG2a
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CD80-2021H Recombinant Human CD80 protein, His-tagged HEK293 His
    Human CD80-363H Recombinant Human CD80 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc
    Human CAB11503MH Mouse Anti-Human CD80 Molecule Monoclonal Antibody Mouse N/A
    Human CD80-0859H Recombinant Human CD80 Protein Wheat Germ N/A
    Human CD80-0860H Recombinant Human CD80 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
    Human CD80-0864H Recombinant Human CD80 Protein, GST-Tagged Wheat Germ GST
    Human CD80-10117H Recombinant Human CD80, GST-tagged E.coli GST
    Human CD80-110H Recombinant Human CD80 Protein, DDK/His-tagged HEK293 DDK/His
    Human CD80-1280H Recombinant Human CD80 protein, Avi & His-tagged, Biotinylated HEK293 Avi/His
    Human CD80-148H Recombinant Human CD80, Fc-tagged CHO Fc
    Human CD80-216H Recombinant Human CD80 Protein, His-tagged Insect Cell His
    Human CD80-2715HCL Recombinant Human CD80 cell lysate Human Cell N/A
    Human CD80-27510TH Recombinant Human CD80, Fc-tagged Fc
    Human CD80-3114H Recombinant Human CD80 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CD80-54H Recombinant Human CD80 Molecule, Fc-Tagged Human Cell Fc
    Human CD80-558H Recombinant Human CD80 protein, His/Fc-tagged NS0 His
    Human CD80-55H Recombinant Human CD80 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc
    Human CD80-560H Recombinant Human CD80 protein, His-tagged NS0 His
    Human CD80-581H Recombinant Human CD80, His-tagged, Biotinylated Human Cell His
    Human CD80-582H Recombinant Human CD80, Fc-tagged, Biotinylated Human Cell Fc
    Human CD80-583H Recombinant Human CD80 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc
    Human CD80-589H Recombinant Human CD80, Fc-His tagged Human Cell Fc/His
    Human CD80-590H Recombinant Human CD80, None tagged Human Cell N/A
    Human CD80-591H Recombinant Human CD80, His tagged Human Cell His
    Human CD80-616H Recombinant Human CD80, MIgG2a Fc-tagged CHO Fc
    Human CD80-617H Recombinant Human CD80, HIgG1 Fc-tagged CHO Fc
    Mouse Cd80-1705M Recombinant Mouse CD80 Antigen NSO N/A
    Mouse CD80-1767MCL Recombinant Mouse CD80 cell lysate Human Cell N/A
    Mouse Cd80-5171M Recombinant Mouse Cd80 protein, His-tagged HEK293 His
    Mouse CD80-626M Recombinant Mouse CD80, MIgG2a Fc-tagged CHO Fc
    Mouse Cd80-6893M Recombinant Mouse Cd80 protein, His & GST-tagged E.coli His/GST
    Mouse Cd80-6898M Recombinant Mouse Cd80 protein, Fc-tagged HEK293 human/IgG1/Fc
    Rat Cd80-1068R Recombinant Rat Cd80 Protein, Fc-tagged HEK293 Fc
    Rat Cd80-217R Recombinant Rat Cd80, Fc Chimera NS0 Fc Chimera
    Cynomolgus Monkey CD80-1213C Recombinant Cynomolgus CD80 Protein, His-tagged HEK293 His
    Cynomolgus/Rhesus macaque CD80-137C Recombinant Cynomolgus/Rhesus macaque CD80 protein, Fc-tagged HEK293 human/IgG1/Fc
    Cynomolgus/Rhesus macaque CD80-274C Recombinant Cynomolgus/Rhesus macaque CD80 protein, His-tagged (HPLC-verified) HEK293 His
    Cynomolgus Monkey CD80-948CCL Recombinant Cynomolgus CD80 cell lysate Human Cell N/A
    Rhesus monkey CD80-1512R Recombinant Rhesus Monkey CD80 Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey CD80-1513R Recombinant Rhesus Monkey CD80 Protein, hIgG4-tagged HEK293 hIgG4
    Rhesus Macaque CD80-749R Recombinant Rhesus monkey CD80 Protein, His-tagged Mammalian Cell His
    Chicken CD80-3572C Recombinant Chicken CD80 Mammalian Cell His

    Cd80 involved in several pathways and played different roles in them. We selected most pathways Cd80 participated on our site, such as Cell adhesion molecules (CAMs), Toll-like receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd80 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) NRCAMA; CD8A; JAM2A; HLA-DQA1; CD8B; CNTNAP2; CLDN3; VCAM1; PVRL3B; CLDN10
    Toll-like receptor signaling pathway PIK3CB; TLR2-2; IFNA7; IL1B; TBK1; TLR7; MAP2K1; IRF7; MAP2K4B; Ifna11
    Intestinal i HLA-DRB3; HLA-DQB1; HLA-DRA; HLA-DMB; H2-AA; HLA-DRB4; CCL27B; CD40LG; HLA-DPA1; CD40
    ne network for IgA production HLA-DMB; BMA1; HLA-DRB1; Icosl; AICDA; HLA-DOA; MHC2DAB; MADCAM1; Il2; TNFRSF17
    Type I diabetes mellitus HLA-A; HLA-C; IL1B; HLA-DRB5; HLA-DQB1; INS1; PTPRN2; GZMB; HLA-DRB4; H2-Q10
    Autoi HLA-DPB1; IL5; HLA-B; HLA-DOA; IFNA1; Fasl; IFNA21; IFNA12; IFNA14; GZMB
    ne thyroid disease HLA-DMA; HLA-DPB1; IFNA2; HLA-DRB5; HLA-DRB4; IFNA12; CD80; HLA-G; HLA-DRB1; HLA-DQA2
    Systemic lupus erythematosus HIST2H2BE; HIST1H3H; H2AFB1; CD40LG; HIST1H2BH; H2AFY; HIST1H3D; ACTN3; GM14483; HIST1H3C
    Rheumatoid arthritis ATP6V0C; CTLA4; IL1A; ATP6V0D2; IL18; IL17A; ATP6V1B2; CXCL1; ITGB2; Ccl12
    Allograft rejection CD40LG; IL12B; HLA-DQA2; GZMB; IL4; HLA-DQA1; H2-AA; HLA-DPB1; Il2; HLA-DRB5
    Graft-versus-host disease HLA-DRB3; HLA-G; KLRC1; Il2; H2-AA; HLA-C; PRF1; HLA-B; HLA-DPA1; KIR2DL3
    Viral myocarditis CD40LG; CD40; H2-AA; CCND1; SGCG; HLA-C; HLA-DQA1; HLA-DRB5; ACTB; RAC2

    Cd80 has several biochemical functions, for example, coreceptor activity, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd80 itself. We selected most functions Cd80 had, and list some proteins which have the same functions with Cd80. You can find most of the proteins on our site.

    Function Related Protein
    coreceptor activity ACKR3B; CXCR7; CXCR4; CD8B; CXCR6; RAMP3; RAMP2; CD8A; CXCR7B; RAMP1
    protein binding MTAP; FAM46D; ERCC3; CIC; TIMM8A; ZNF205; GLS2; CLC; CD79B; PLK1
    virus receptor activity HAVCR1; ITGAV; RPSA; IDE; DPP4; NCAM1; CD4; HTR2A; TNFRSF4; CD209A

    Cd80 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd80 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd80.

    CTLA4; NGFR; CD28; CD86; CD274

    Sagiv-Barfi, I; Kohrt, HEK; et al. Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E966-E972(2015).
    Garin, EH; Reiser, J; et al. Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis. PEDIATRIC NEPHROLOGY 30:469-477(2015).

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