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Cd80

  • Official Full Name

    CD80 antigen

  • Overview

    Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor. The protein CD80 (Cluster of Differentiation 80) is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. It is also known as B7.1. Its principal mode of action is by bindin
  • Synonyms

    CD80; CD80 antigen; B71; Ly53; TSA1; Cd28l; Ly-53; MIC17; T-lymphocyte activation antigen CD80; B7 protein; activation B7-1 antigen; B7; BB1; LAB7; CD28LG; CD28LG1; OTTHUMP00000215214; OTTHUMP00000215215; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • GMP Proteins
  • Chicken
  • Cynomolgus
  • Cynomolgus monkey
  • Cynomolgus Monkey
  • Cynomolgus/Rhesus macaque
  • Homo sapiens (Human)
  • Human
  • Monkey
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rabbit
  • Rat
  • Rhesus Macaque
  • Rhesus monkey
  • CHO
  • CHO cells
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293F
  • HEK293T
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • In vitro E. coli expression system
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Mouse
  • Wheat Germ
  • 5 amino acids
  • Avi|Fc
  • Avi|His
  • C
  • Fc
  • hFc
  • His
  • Avi
  • DDK|His
  • Fc Chimera
  • Fc|His
  • His(C
  • ter)
  • Flag
  • GPI
  • Strep
  • GST
  • Myc
  • hIgG1
  • hIgG4
  • His (Fc)
  • His|Flag|StrepII
  • His|GST
  • human|IgG1|Fc
  • Mouse|IgG2a|Fc
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD80-558H Active Recombinant Human CD80 protein, His/Fc-tagged Mammalian cells His Val35-Asn242
Human CD80-560H Active Recombinant Human CD80 protein, His-tagged Mammalian cells His Val35-Asn242
Human CD80-617H Active Recombinant Human CD80, HIgG1 Fc-tagged CHO Fc
Human CD80-583H Active Recombinant Human CD80 Protein, Fc & Avi-tagged, Biotinylated HEK293 Avi/Fc Val 35 - Asn 242
Human CD80-581H Active Recombinant Human CD80, His-tagged, Biotinylated Human Cell His
Human CD80-616H Active Recombinant Human CD80, MIgG2a Fc-tagged CHO Fc
Human CD80-582H Active Recombinant Human CD80, Fc-tagged, Biotinylated Human Cell Fc
Human CD80-051H Active Recombinant Human CD80 protein, Fc/Avi-tagged, Biotinylated CHO cells Fc/Avi Val35-Asn242
Human CD80-052H Active Recombinant Human CD80 protein, His/Avi-tagged, Biotinylated CHO cells His/Avi Val35-Asn242
Human CD80-1376H Acitve Recombinant Human CD80 protein(Met1-Asn242), His&Avi-tagged, Biotinylated HEK293 C-His&Avi Met1-Asn242
Human CD80-591H Active Recombinant Human CD80 protein, His-tagged HEK293 His Met1-Asn242
Human CD80-590H Recombinant Human CD80 protein HEK293 N/A Met1-Asn242
Human CD80-0860H Recombinant Human CD80 Protein, His-Flag-StrepII-Tagged Human Cell His/Flag/StrepII
Human CD80-0859H Recombinant Human CD80 Protein Wheat Germ N/A
Human CD80-10117H Recombinant Human CD80, GST-tagged E.coli GST 36-228a.a.
Human CD80-110H Recombinant Human CD80 Protein, DDK/His-tagged HEK293 DDK/His Val35-Asn242
Human CD80-0864H Recombinant Human CD80 Protein, GST-Tagged Wheat Germ GST
Human CD80-54H Recombinant Human CD80 Molecule, Fc-Tagged Human Cell Fc
Human CD80-589H Recombinant Human CD80, Fc-His tagged Human Cell Fc/His
Human CD80-27510TH Recombinant Human CD80, Fc-tagged Fc
Human CD80-148H Recombinant Human CD80, Fc-tagged CHO Fc
Human CD80-55H Recombinant Human CD80 protein, Fc-tagged (HPLC-verified) HEK293 human/IgG1/Fc 208
Human CD80-2715HCL Recombinant Human CD80 cell lysate Human Cell N/A
Human CD80-2407H Recombinant Human CD80 Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 35-288aa
Human CD80-589HAF647 Recombinant Human CD80 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His 455
Human CD80-3114H Recombinant Human CD80 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CAB11503MH Mouse Anti-Human CD80 Molecule Monoclonal Antibody Mouse N/A
Human CD80-190H Recombinant Human CD80 protein, His-Avi-tagged HEK293 His-Avi It contains Val35-Asn242.
Human CD80-590HAF647 Recombinant Human CD80 Protein, Alexa Fluor 647 conjugated HEK293 5 amino acids 214
Human CD80-2021H Recombinant Human CD80 protein, His-tagged HEK293 His Val35-Asn242
Human CD80-152H Recombinant Human CD80 Protein, His-tagged Human Cells His
Human CD80-589HAF488 Recombinant Human CD80 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His 455
Human CD80-591HAF647 Recombinant Human CD80 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 219
Human CD80-590HAF488 Recombinant Human CD80 Protein, Alexa Fluor 488 conjugated HEK293 5 amino acids 214
Human CD80-700H Recombinant Human CD80 Protein, His-tagged HEK293F N-His Val35-Asn242
Human CD80-547H Recombinant Human CD80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD80-589HF Recombinant Human CD80 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His 455
Human CD80-591HAF488 Recombinant Human CD80 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 219
Human CD80-185H Recombinant Human CD80 Protein, C-His-tagged E.coli C-His
Human CD80-588H Recombinant Human CD80 Protein HEK293 288
Human CD80-590HF Recombinant Human CD80 Protein, FITC conjugated HEK293 5 amino acids 214
Human CD80-4997H Recombinant Human CD80 protein, hFc-Myc-tagged HEK293 hFc-Myc 35-242aa
Human CD80-1232HFL Recombinant Full Length Human CD80 Protein, C-Flag-tagged Mammalian cells Flag
Human CD80-547H-B Recombinant Human CD80 Protein Pre-coupled Magnetic Beads HEK293
Human CD80-591HF Recombinant Human CD80 Protein, His-tagged, FITC conjugated HEK293 His 219
Human CD80-3069HF Recombinant Full Length Human CD80 Protein, GST-tagged In Vitro Cell Free System GST 35-288 amino acids
Human CD80-530H Recombinant Human CD80 Protein (Val35-Asn242), C-hFc-tagged HEK293 C-hFc Val35-Asn242
Human CD80-0931H Recombinant Human CD80 Protein (Met1-Asn242), C-His tagged Mammalian cells C-His Met1-Asn242
Human CD80-3061HF Recombinant Full Length Human CD80 Protein In Vitro Cell Free System 520 amino acids
Human CD80-0962H Recombinant Human CD80 Protein (Val35-Asn242), N-His tagged E.coli N-His Val35-Asn242
Human CD80-589HAF555 Recombinant Human CD80 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His 455
Human CD80-0268H Recombinant Human CD80 protein, His-tagged, Biotinylated HEK293 His Met1-Asn242
Human CD80-590HAF555 Recombinant Human CD80 Protein, Alexa Fluor 555 conjugated HEK293 5 amino acids 214
Human CD80-591HAF555 Recombinant Human CD80 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 219
Human CD80-216H Recombinant Human CD80 Protein, His-tagged Insect Cell His 35-242aa
Human CD80-1280H Recombinant Human CD80 protein, Avi & His-tagged, Biotinylated HEK293 Avi/His Val 35 - Asn 242
Human CD80-363H Recombinant Human CD80 protein, Mouse IgG2a Fc-tagged, low endotoxin HEK293 Mouse/IgG2a/Fc 208
Human CD80-085HG Active GMP Recombinant Human CD80 protein HEK293 DNA sequence encoding NP_005182.1 was expressed with His tag at the C-terminal.
Human CD80-38H Recombinant Human CD80 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Val35-Asn242
Mouse CD80-626M Active Recombinant Mouse CD80, MIgG2a Fc-tagged CHO Fc
Mouse CD80-1347M Acitve Recombinant Mouse CD80 protein(Met1-Lys245), hFc-tagged HEK293 C-hFc Met1-Lys245
Mouse Cd80-6893M Recombinant Mouse Cd80 protein, His & GST-tagged E.coli His/GST Asp39~Asn246 (Accession # Q00609)
Mouse Cd80-5171M Active Recombinant Mouse Cd80 protein(Met1-Lys245), His-tagged HEK293 C-His Met1-Lys245
Mouse Cd80-1705M Recombinant Mouse CD80 Antigen Mammalian cells N/A
Mouse Cd80-6898M Recombinant Mouse Cd80 protein, Fc-tagged HEK293 human/IgG1/Fc Val38-Lys245
Mouse CD80-1767MCL Recombinant Mouse CD80 cell lysate Human Cell N/A
Mouse Cd80-36M Recombinant Mouse CD80 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Val38-Lys245
Mouse Cd80-6898MAF488 Recombinant Mouse Cd80 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc Val38-Lys245
Mouse Cd80-6898MF Recombinant Mouse Cd80 Protein, hFc-tagged, FITC conjugated HEK293 hFc Val38-Lys245
Mouse Cd80-848M Recombinant Mouse Cd80 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Cd80-37M Recombinant Mouse CD80 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Val38-Lys245
Mouse CD80-1370M Recombinant Mouse CD80 protein(Met1-Lys245), His-tagged, Biotinylated HEK293 C-His Met1-Lys245
Mouse Cd80-5171MAF488 Recombinant Mouse Cd80 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His Val38-Lys245
Mouse CD80-591M Recombinant Mouse CD80 Protein, Fc-tagged HEK293 Fc 306
Mouse Cd80-5171MF Recombinant Mouse Cd80 Protein, His-tagged, FITC conjugated HEK293 His Val38-Lys245
Mouse Cd80-6898MAF647 Recombinant Mouse Cd80 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc Val38-Lys245
Mouse Cd80-6898MAF555 Recombinant Mouse Cd80 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc Val38-Lys245
Mouse Cd80-4008M Recombinant Mouse Cd80 Protein (Val38-Asn246), GPI and C-Strep tagged Mammalian cells GPI and C-Strep Val38-Asn246
Mouse Cd80-5171MAF555 Recombinant Mouse Cd80 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His Val38-Lys245
Mouse Cd80-5622M Recombinant Mouse Cd80 Protein (Val38-Lys245), C-Fc tagged Mammalian cells C-Fc Val38-Lys245
Mouse Cd80-4007M Recombinant Mouse Cd80 Protein (Val38-Asn246), GPI and C-His tagged Mammalian cells GPI and C-His Val38-Asn246
Mouse Cd80-5171MAF647 Recombinant Mouse Cd80 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His Val38-Lys245
Mouse CD80-590M Recombinant Mouse CD80 Protein HEK293 306
Mouse Cd80-5623M Recombinant Mouse Cd80 Protein (Val38-Asn246), C-His tagged Mammalian cells C-His Val38-Asn246
Mouse Cd80-10528M-B Recombinant Mouse Cd80 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cd80-10528M Recombinant Mouse Cd80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cd80-217R Active Recombinant Rat Cd80, Fc Chimera Mammalian cells Fc Chimera
Rat Cd80-1068R Recombinant Rat Cd80 Protein, Fc-tagged HEK293 Fc
Rat CD80-1874R Active Recombinant Rat CD80 protein, His-tagged HEK293 His Ile 39 - Gln 248
Rat Cd80-1068RAF488 Recombinant Rat Cd80 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 451
Rat Cd80-1068RAF555 Recombinant Rat Cd80 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 451
Rat Cd80-6836R Recombinant Rat Cd80 Protein (Vla30-Gln248), C-His tagged Mammalian cells C-His Vla30-Gln248
Rat Cd80-1068RF Recombinant Rat Cd80 Protein, Fc-tagged, FITC conjugated HEK293 Fc 451
Rat Cd80-1068RAF647 Recombinant Rat Cd80 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 451
Rat Cd80-1271R Recombinant Rat Cd80 Protein, His-tagged E.coli N-His Gly41-Gln248
Rat Cd80-24R Recombinant Rat Cd80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Cd80-24R-B Recombinant Rat Cd80 Protein Pre-coupled Magnetic Beads HEK293
Monkey CD80-137CAF647 Recombinant Monkey CD80 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc Val35-Asn242
Monkey CD80-1213CF Recombinant Cynomolgus CD80 Protein, His-tagged, FITC conjugated HEK293 His 219
Monkey CD80-1213CAF647 Recombinant Cynomolgus CD80 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 219
Monkey CD80-137CAF488 Recombinant Monkey CD80 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc Val35-Asn242
Monkey CD80-137CAF555 Recombinant Monkey CD80 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc Val35-Asn242
Monkey CD80-1213CAF555 Recombinant Cynomolgus CD80 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 219
Monkey CD80-1213CAF488 Recombinant Cynomolgus CD80 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 219
Monkey CD80-137CF Recombinant Monkey CD80 Protein, hFc-tagged, FITC conjugated HEK293 hFc Val35-Asn242
Rhesus monkey CD80-1513R Recombinant Rhesus Monkey CD80 Protein, hIgG4-tagged HEK293 hIgG4
Rhesus monkey CD80-1512R Recombinant Rhesus Monkey CD80 Protein, hIgG1-tagged HEK293 hIgG1
Rabbit CD80-5398R Recombinant Rabbit CD80 Protein (Gly33-Gln241), C-His tagged Mammalian cells C-His Gly33-Gln241
Cynomolgus CD80-1028C Recombinant Cynomolgus CD80 protein, His-tagged HEK293 His Val 35 - Asn 242
Cynomolgus Monkey CD80-1213C Recombinant Cynomolgus CD80 Protein, His-tagged HEK293 His
Cynomolgus Monkey CD80-948CCL Recombinant Cynomolgus CD80 cell lysate Human Cell N/A
Cynomolgus monkey CD80-587C Recombinant Cynomolgus monkey CD80 Protein, Fc-tagged HEK293 Fc 288
Cynomolgus monkey CD80-586C Recombinant Cynomolgus monkey CD80 Protein HEK293 288
Cynomolgus/Rhesus macaque CD80-2930C Active Recombinant Cynomolgus/Rhesus macaque CD80 protein, Fc-tagged HEK293 Fc Val 35-Asn 242
Cynomolgus/Rhesus macaque CD80-137C Recombinant Cynomolgus/Rhesus macaque CD80 protein, Fc-tagged HEK293 human/IgG1/Fc Val35-Asn242
Cynomolgus/Rhesus macaque CD80-274C Recombinant Cynomolgus/Rhesus macaque CD80 protein, His-tagged (HPLC-verified) HEK293 His Val35-Asn242
Homo sapiens (Human) RFL8683HF Recombinant Full Length Human T-Lymphocyte Activation Antigen Cd80(Cd80) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (35-288aa)
Homo sapiens (Human) RFL974HF Recombinant Full Length Human T-Lymphocyte Activation Antigen Cd80(Cd80) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (35-288)
Mus musculus (Mouse) RFL1323MF Recombinant Full Length Mouse T-Lymphocyte Activation Antigen Cd80(Cd80) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (38-306)
Oryctolagus cuniculus (Rabbit) RFL4268OF Recombinant Full Length Rabbit T-Lymphocyte Activation Antigen Cd80(Cd80) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (33-299)
Rhesus Macaque CD80-749R Recombinant Rhesus monkey CD80 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD80-575R Recombinant Rhesus Macaque CD80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CD80-575R-B Recombinant Rhesus Macaque CD80 Protein Pre-coupled Magnetic Beads HEK293
Chicken CD80-3572C Recombinant Chicken CD80 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Cd80 Related Articles
  • Cd80 Related Gene Family
  • Cd80 Related Research Area

Cd80 involved in several pathways and played different roles in them. We selected most pathways Cd80 participated on our site, such as Cell adhesion molecules (CAMs), Toll-like receptor signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd80 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CLDND;CLDNE;CD274;ITGB2;BF2;HLA-DOB;F11R;CD2;CD8B1
Toll-like receptor signaling pathwayRAC1;RIPK1;CD80;RAC1B;CD86;MAPK14A;STAT1A;TLR5;MAPK12
Intestinal iMHC2DAB;IL6;CD40LG;HLA-DQA2;IL15RA;TNFRSF13B;CCL27B;H2-AB1;BMA1
ne network for IgA productionCXCR4;CCR10;CXCL12;PIGR;BLA;CD28;TNFRSF17;CXCL12A;BLB1
Type I diabetes mellitusH2-Q10;GAD1;INS;TNF;Il2;HLA-DQB1;GAD2;HLA-DRA;HLA-E
AutoiHLA-DRA;HLA-E;CD40;FASLG;HLA-G;TSHR;HLA-DOB;IFNA1;H2-Q10
ne thyroid diseaseIFNA17;H2-AA;Il2;CD86;FAS;HLA-DRB1;IFNA1;IFNA5;FASLG
Systemic lupus erythematosusHIST1H2BB;GM14483;HIST1H2BJ;HIST1H2BF;HIST2H2BE;HIST1H4H;TRIM21;HIST1H2BM;HIST1H4C
Rheumatoid arthritisATP6V0E1;TLR2;ITGB2;Ctsl;HLA-DOA;ATP6V0A4;HLA-DMB;HLA-DQA1;TNFSF13B
Allograft rejectionHLA-DMA;CD28;HLA-E;FAS;CD86;IL10;IFNG;HLA-DQB1;H2-Q10
Graft-versus-host diseaseIL1B;FAS;HLA-C;CD86;HLA-DMB;HLA-G;HLA-DRB5;Fasl;KIR2DL1
Viral myocarditisCAV1;ITGB2;HLA-DOB;HLA-DQB1;ICAM1;CASP8;CCND1;HLA-DQA1;EIF4G2

Cd80 has several biochemical functions, for example, coreceptor activity, protein binding, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd80 itself. We selected most functions Cd80 had, and list some proteins which have the same functions with Cd80. You can find most of the proteins on our site.

Function Related Protein
coreceptor activityRAMP1;LRP5;CXCR7B;CXCR6;TGFBR3;RAMP2;CCR5;RGMB;CD4
protein bindingBRCA1;HSPB1;PLAA;APOBEC3F;LCORL;SETD7;ACACB;GGN;CAMK2A
virus receptor activityTFRC;HYAL2;HSPA1A;PVRL2;F11R;SELPLG;SIVA1;CLEC5A;MOG

Cd80 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd80 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd80.

CTLA4; NGFR; CD28; CD86; CD274

Sagiv-Barfi, I; Kohrt, HEK; et al. Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E966-E972(2015).
Garin, EH; Reiser, J; et al. Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis. PEDIATRIC NEPHROLOGY 30:469-477(2015).
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