IL9 Protein, interleukin 9

IL9

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IL9

Official Full Name interleukin 9
Background The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Synonyms IL9; interleukin 9; P40; HP40; IL-9; interleukin-9; cytokine P40; p40 cytokine; TTHUMP00000159423; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • Hordeum Vulgare
    • Insect Cell
    • Mammalian Cell
    • Mouse
    • NS0
    • Sf21 Insect Cell
    • Wheat Germ
    • Tag :
    • Alexa Fluor 647
    • Biotin
    • Fc
    • GST
    • His
    • T7
    • HQ
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Il9-119M Recombinant Mouse Il9 Protein E.coli
    Mouse IL9-858M Recombinant Mouse IL9 Protein (Met1-Pro144), His-tagged Insect Cell His
    Human DMABT-H19268 Mouse Anti-IL9 Monoclonal Antibody Mouse Biotin
    Human DMABT-H19269 Mouse Anti-IL9 Monoclonal Antibody Mouse Alexa Fluor 647
    Human DMABT-H19270 Mouse Anti-IL9 Monoclonal Antibody Mouse Biotin
    Human Il9-001H Recombinant Human Il9, HIgG1 Fc-tagged, mutant CHO Fc
    Human Il9-002H Recombinant Human Il9, HIgG1 Fc-tagged CHO Fc
    Human IL9-003H Recombinant Human IL9, MIgG2a Fc-tagged CHO Fc
    Human IL9-115H Human Interleukin-9 (rDNA derived) Reference standard N/A
    Human IL9-14214H Recombinant Human IL9, GST-tagged E.coli GST
    Human IL9-216H Recombinant Human Interleukin 9 Sf21 Insect Cell N/A
    Human IL9-28162TH Recombinant Human IL9, His-tagged His
    Human IL9-374H Recombinant Human IL9, His tagged Insect Cell His
    Human IL9-4324HG GMP Recombinant Human IL9 protein E.coli N/A
    Human IL9-476H Recombinant Human Interleukin 9 E.coli N/A
    Human IL9-5165H Recombinant Human IL9 Protein, GST-tagged Wheat Germ GST
    Human IL9-5342H Recombinant Human Interleukin 9, HQ-tagged Hordeum Vulgare HQ
    Human IL9-618HCL Recombinant Human IL9 cell lysate Insect Cell N/A
    Human IL9-668H Recombinant Human IL9 protein, His & T7-tagged E.coli His/T7
    Human IL9-67H Recombinant Human IL9 protein E.coli N/A
    Human IL9-8866H Recombinant Human IL9,His-tagged Hordeum Vulgare N/A
    Mouse Il9-001M Recombinant Mouse Il9, MIgG2a Fc-tagged, mutant CHO Fc
    Mouse Il9-002M Recombinant Mouse Il9, MIgG2a Fc-tagged CHO Fc
    Mouse Il9-2175M Recombinant Mouse Il9 Protein E.coli N/A
    Mouse Il9-225M Recombinant Mouse Interleukin 9 Sf21 Insect Cell N/A
    Mouse Il9-477M Recombinant Mouse Interleukin 9 E.coli N/A
    Mouse Il9-78M Recombinant Mouse Il9 protein E.coli N/A
    Mouse IL9-8181M Recombinant Mouse IL9 Protein Mammalian Cell His
    Rat Il9-1117R Recombinant Rat Il9 Protein, His-tagged Insect Cell His
    Rat Il9-2171R Recombinant Rat Il9 protein E.coli N/A
    Rat Il9-676R Recombinant Rat Il9 NS0 N/A
    Chicken IL9-3294C Recombinant Chicken IL9 Mammalian Cell His

    IL9 involved in several pathways and played different roles in them. We selected most pathways IL9 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Asthma, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CRFB4; IFNA5; TNFRSF9; IL1B; CSF1; LTA; CCL18; LTB; IL1A; GH1
    Jak-STAT signaling pathway IFNA6; IL21R.1; TYK2; MTOR; IL21; CCND1; IL13; IRX1; IL24; IL11RA2
    Asthma HLA-DOB; CCL11; IL13; IL9; MS4A2; PRG2; CD40; HLA-DRB3; HLA-DQB1; HLA-DPB1

    IL9 has several biochemical functions, for example, cytokine activity, growth factor activity, interleukin-9 receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by IL9 itself. We selected most functions IL9 had, and list some proteins which have the same functions with IL9. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity GDF3; IFNA12; IFNA7; IFNA16; ADIPOQ; CD70; CCL38.1; IL8L2; IL23; TNFRSF11B
    growth factor activity VEGFA; FGF11; FGF22; FGF8; IL8L2; Artn; GDF10; IL5; CD320; NDP
    interleukin-9 receptor binding IL9

    IL9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL9 here. Most of them are supplied by our site. Hope this information will be useful for your research of IL9.

    Venetz, D; Hess, C; et al. Glycosylation profiles determine extravasation and disease-targeting properties of armed antibodies. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:2000-2005(2015).
    Hoelzinger, DB; Dominguez, AL; et al. Inhibition of Adaptive Immunity by IL9 Can Be Disrupted to Achieve Rapid T-cell Sensitization and Rejection of Progressive Tumor Challenges. CANCER RESEARCH 74:6845-6855(2014).

    IL

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