mmp3
Share
  • Official Full Name
  • matrix metallopeptidase 3 (stromelysin 1, progelatinase)
  • Background
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
  • Synonyms
  • MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1; CHDS6; MMP-3; STMY1; stromelysin-1; transin-1; proteoglycanase; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, progelatinase)
Cat.#:MMP3-5433HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MMP3 Protein, GST-tagged
+Inquiry
Cat.#:MMP3-555HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human MMP3 Protein, MYC/DDK-tagged
+Inquiry
Cat.#:MMP3-1383HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase), GST-Tagged
+Inquiry
Cat.#:MMP3-163HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP3 (Stromelysin 1, Progelatinase), Inactive, Catalytic Domain
+Inquiry
Cat.#:MMP3-197HTag:
Source (Host):Species:Human
Product nameRecombinant Human MMP3
+Inquiry
Cat.#:MMP3-200HTag:His
Source (Host):Species:Human
Product nameRecombinant Human MMP3, His-tagged
+Inquiry
Cat.#:MMP3-39HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP3
+Inquiry
Cat.#:MMP3-049HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Matrix Metallopeptidase 3 (stromelysin 1, progelatinase)
+Inquiry
Cat.#:MMP3-152HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Matrix Metallopeptidase 3, Catalytic Domain
+Inquiry
Cat.#:MMP3-224HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP3 Protein
+Inquiry
Cat.#:MMP3-28202THTag:His
Source (Host):Species:Human
Product nameRecombinant Human MMP3, His-tagged
+Inquiry
Cat.#:MMP3-479HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human matrix metallopeptidase 3 (stromelysin 1, progelatinase), His-tagged
+Inquiry
Cat.#:MMP3-5080HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MMP3, His-tagged
+Inquiry
Cat.#:MMP3-740HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human MMP3 Protein, His-tagged
+Inquiry
Cat.#:Mmp3-416MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Mmp3 protein
+Inquiry
Cat.#:Mmp3-743MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mmp3 protein, His & T7-tagged
+Inquiry
Cat.#:MMP3-9924MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MMP3 Protein
+Inquiry
Cat.#:Mmp3-745RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mmp3 protein, His-tagged
+Inquiry
Cat.#:MMP3-739CTag:His/T7
Source (Host):E. coliSpecies:Cattle
Product nameRecombinant Cattle MMP3 protein, His & T7-tagged
+Inquiry
Cat.#:MMP3-744PTag:His/T7
Source (Host):E. coliSpecies:Pig
Product nameRecombinant Pig MMP3 protein, His & T7-tagged
+Inquiry
Cat.#:MMP3-26CTag:
Source (Host):Species:Clostridium histolyticum
Product nameCollagenase Type 3 Protein
+Inquiry
Cat.#:MMP3-4273HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MMP3 293 Cell Lysate
+Inquiry

Involved Pathway

MMP3 involved in several pathways and played different roles in them. We selected most pathways MMP3 participated on our site, such as TNF signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
TNF signaling pathway
TRAF1; PIK3R5; CREB3L3; BAG4; PIK3CG; CASP7; VCAM1; CCL5; NFKB1; MAPK12
Transcriptional misregulation in cancer
MAX; H3F3B; LYL1; TMPRSS2; TAF15; HIST1H3A; RXRB; MDM2; GRIA3; LMO2
Rheumatoid arthritis
CXCL12; ATP6V0D2; ATP6V1A; FLT1; CD80; ATP6V0B; TLR2; Il23a; Il12b; ATP6V0D1; ATP6V1B2

Protein Function

MMP3 has several biochemical functions, for example, calcium ion binding, endopeptidase activity, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP3 itself. We selected most functions MMP3 had, and list some proteins which have the same functions with MMP3. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein ANXA13; SPOCK2; PROC; CAPN1; CRB2; PLA2G5; MMP19; MYLPFA; CABP5A; PPP3R1
Function endopeptidase activity
Related Protein KLK1B5; ADAM10; CD46; PSMB8; KLK1B4; CASP1; TPP2; KLK1B16; KLK1B24; KLK1B11
Function metalloendopeptidase activity
Related Protein ZMPSTE24; MMP11; UQCRC2B; MMP13; ADAM17; MBTPS2; MMP9; MEP1B; ADAM7; ADAMDEC1
Function protein binding
Related Protein HECTD3; HNRNPA1; CDKN1A; SP140; DNMT1; SKAP2; SECISBP2; IFRD2; LGALS13; C4orf26
Function zinc ion binding
Related Protein SQSTM1; POLR2K; RFWD2; CHMP1A; SIRT3; USP33; MMP20; ABLIM1A; EHMT1; TRAF4

Interacting Protein

MMP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP3.
MEOX2; TIMP1

MMP3 Related Gene Family

MMPs