MMP3 Protein, matrix metallopeptidase 3 (stromelysin 1, progelatinase)

MMP3

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MMP3

Official Full Name matrix metallopeptidase 3 (stromelysin 1, progelatinase)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Synonyms MMP3; matrix metallopeptidase 3 (stromelysin 1, progelatinase); SL-1; STMY; STR1; CHDS6; MMP-3; STMY1; stromelysin-1; transin-1; proteoglycanase; matrix metalloproteinase-3; matrix metalloproteinase 3 (stromelysin 1, progelatinase)
    • Species :
    • Cattle
    • Clostridium histolyticum
    • Human
    • Mouse
    • Pig
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MMP3-049H Recombinant Human Matrix Metallopeptidase 3 (stromelysin 1, progelatinase) E.coli N/A
    Human MMP3-1383H Recombinant Human Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase), GST-Tagged Human GST
    Human MMP3-152H Recombinant Human Matrix Metallopeptidase 3, Catalytic Domain E.coli N/A
    Human MMP3-163H Recombinant Human MMP3 (Stromelysin 1, Progelatinase), Inactive, Catalytic Domain E.coli N/A
    Human MMP3-197H Recombinant Human MMP3 E.coli N/A
    Human MMP3-200H Recombinant Human MMP3, His-tagged HEK293 His
    Human MMP3-224H Recombinant Human MMP3 Protein E.coli N/A
    Human MMP3-28202TH Recombinant Human MMP3, His-tagged His
    Human MMP3-39H Recombinant Human MMP3 E.coli N/A
    Human MMP3-4273HCL Recombinant Human MMP3 293 Cell Lysate HEK293 N/A
    Human MMP3-479H Recombinant Human matrix metallopeptidase 3 (stromelysin 1, progelatinase), His-tagged E.coli His
    Human MMP3-5080H Recombinant Human MMP3, His-tagged E.coli His
    Human MMP3-5433H Recombinant Human MMP3 Protein, GST-tagged Wheat Germ GST
    Human MMP3-555H Recombinant Human MMP3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human MMP3-740H Recombinant Human MMP3 Protein, His-tagged HEK293 His
    Mouse Mmp3-416M Recombinant Mouse Mmp3 protein NS0 N/A
    Mouse Mmp3-743M Recombinant Mouse Mmp3 protein, His & T7-tagged E.coli His/T7
    Mouse MMP3-9924M Recombinant Mouse MMP3 Protein Mammalian Cell His
    Rat Mmp3-745R Recombinant Rat Mmp3 protein, His-tagged E.coli His
    Clostridium histolyticum MMP3-26C Collagenase Type 3 Protein N/A
    Cattle MMP3-739C Recombinant Cattle MMP3 protein, His & T7-tagged E.coli His/T7
    Pig MMP3-744P Recombinant Pig MMP3 protein, His & T7-tagged E.coli His/T7

    MMP3 involved in several pathways and played different roles in them. We selected most pathways MMP3 participated on our site, such as TNF signaling pathway, Transcriptional misregulation in cancer, Rheumatoid arthritis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MMP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TNF signaling pathway FAS; PIK3R3; PIK3CA; TNFAIP3; FOS; AKT1; NFKBIA; MAGI2; IKBKG; MAP2K6
    Transcriptional misregulation in cancer HOXA9; IL1R2; H3F3C; Bcl2a1b; BCL6; PTK2; NUPR1; MAX; IL-8; FCGR1
    Rheumatoid arthritis TEK; ATP6V0E2; ITGB2; IFNG; ATP6V0E; MMP1A; HLA-DQB1; CCL3L1; TNFSF11; HLA-DRB5

    MMP3 has several biochemical functions, for example, calcium ion binding, endopeptidase activity, metalloendopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MMP3 itself. We selected most functions MMP3 had, and list some proteins which have the same functions with MMP3. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding FLG; DHH; RASGRP2; PCDH1G11; OVAL; REPS1; CAPN3B; PPEF1; LDLRB; ANXA3B
    endopeptidase activity APH1B; SENP3; TPP1; HTRA4; NAPSA; SENP1; ACE2; PSMA3; FURIN; PSMB8
    metalloendopeptidase activity MEP1A; UQCRC2; MMP12; C6AST1; ADAMDEC1; MEP1A.1; ADAM33; Adam6; MMP13A; MMP14
    protein binding RAD51; ERC2; CCDC88A; UFD1L; KLK6; ID1; PSMD5; DPCD; BCL2L13; C19orf47
    zinc ion binding ADAM1B; KDM7AB; PHF8; RXRB; SF3A2; KCMF1; ZDHHC14; P2RX4; LTA4H; ESRRGB

    MMP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MMP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MMP3.

    MEOX2; TIMP1

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