tnfrsf18
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  • Official Full Name
  • tumor necrosis factor receptor superfamily, member 18
  • Background
  • This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased;expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance;maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in;the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript;variants of this gene encoding distinct isoforms have been reported.
  • Synonyms
  • TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; glucocorticoid-induced TNFR-related protein; AITR; Gitr
Cat.#:TNFRSF18-2091HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFRSF18 Protein, His-Avi-tagged, Biotinylated
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Cat.#:TNFRSF18-619HTag:Fc-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFRSF18 Protein, Fc-Avi-tagged, Biotinylated
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Cat.#:TNFRSF18-1995HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFRSF18 Protein, MYC/DDK-tagged
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Cat.#:TNFRSF18-1621HTag:Fc
Source (Host):NS0Species:Human
Product nameRecombinant Human TNFRSF18, Fc Chimera
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Cat.#:TNFRSF18-2086HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFRSF18, Fc-tagged
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Cat.#:TNFRSF18-2090HTag:His
Source (Host):Human CellsSpecies:Human
Product nameRecombinant Human TNFRSF18, His-tagged
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Cat.#:TNFRSF18-370HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human TNFRSF18 Protein, His-tagged
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Cat.#:TNFRSF18-39HTag:HIgG/His
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human TNFRSF18 protein, hIgG-His-tagged
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Cat.#:TNFRSF18-554HTag:His/GST
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFRSF18, Fc tagged
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Cat.#:TNFRSF18-618HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human TNFRSF18, Fc-tagged, Biotinylated
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Cat.#:TNFRSF18-925HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TNFRSF18
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Cat.#:Tnfrsf18-15MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Tnfrsf18 protein, His-tagged
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Cat.#:TNFRSF18-17159MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TNFRSF18 Protein
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Cat.#:Tnfrsf18-2087MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Tnfrsf18, Fc Chimera
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Cat.#:Tnfrsf18-8735RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Tnfrsf18, Fc tagged
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Cat.#:Tnfrsf18-01CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant cynomolgus TNFRSF18 protein, His-tagged
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Cat.#:TNFRSF18-1785RTag:
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey TNFRSF18 Protein
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Cat.#:TNFRSF18-1786RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey TNFRSF18 Protein, hIgG1-tagged
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Cat.#:TNFRSF18-1787RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey TNFRSF18 Protein, hIgG4-tagged
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Cat.#:TNFRSF18-29RTag:Fc
Source (Host):HEK293Species:Rhesus macaque
Product nameRecombinant Rhesus macaque TNFRSF18 Protein, Fc-tagged
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Cat.#:TNFRSF18-2565CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TNFRSF18
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Cat.#:TNFRSF18-6312ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TNFRSF18
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Cat.#:TNFRSF18-1143HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human TNFRSF18 cell lysate
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Cat.#:TNFRSF18-1245RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat TNFRSF18 cell lysate
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Cat.#:CSC-P0770Tag:
Source (Host):Species:Human
Product nameAnti-Human TNFRSF18 MAb Stable Cell Line-CHO
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Cat.#:CSC-P0771Tag:
Source (Host):Species:Human
Product nameAnti-Human TNFRSF18 F(ab) Stable Cell Line-CHO
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Cat.#:CSC-P0772Tag:
Source (Host):Species:Human
Product nameAnti-Human TNFRSF18 scFv Stable Cell Line-CHO
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Involved Pathway

Tnfrsf18 involved in several pathways and played different roles in them. We selected most pathways Tnfrsf18 participated on our site, such as Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Tnfrsf18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
OSM; ACVR1L; Ifnlr1; IFNL3; EPOR; GH1; IL11RA2; CXCL10; CCL19B; CCL1

Protein Function

Tnfrsf18 has several biochemical functions, for example, tumor necrosis factor-activated receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Tnfrsf18 itself. We selected most functions Tnfrsf18 had, and list some proteins which have the same functions with Tnfrsf18. You can find most of the proteins on our site.
Function
Related Protein
Function tumor necrosis factor-activated receptor activity
Related Protein TNFRSF25; TNFRSF8; LTBR; NGFRB; TNFRSF19; TNFRSF10B; TNFRSF11B; TNFRSF14; CD27; TNFRSF18

Interacting Protein

Tnfrsf18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Tnfrsf18 here. Most of them are supplied by our site. Hope this information will be useful for your research of Tnfrsf18.
MYC

Tnfrsf18 Related Gene Family

TNF Cytokines