Active Recombinant Mouse Mog Protein, His-tagged

• Cat.No.: Mog-02M
• Product Overview: Recombinant Mouse Mog Protein (Gly29-Gly153), with a C-terminal 10-His tag, was expressed in mouse myeloma cell line.

Specification

• Description: Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to act upstream of or within cell adhesion. Located in myelin sheath. Is expressed in brain and cerebellum. Human ortholog(s) of this gene implicated in multiple sclerosis; narcolepsy; and optic neuritis. Orthologous to human MOG (myelin oligodendrocyte glycoprotein).
• Source: Mouse myeloma cell line
• Species: Mouse
• Tag: His
• Bio-activity: Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Recombinant Mouse MOG, immobilized at 1 μg/mL on a 96-well plate, is able to significantly enhance neurite outgrowth.
• Molecular Mass: 19-29 kDa
• N-terminal Sequence Analysis: Gly29
• Endotoxin: < 0.10 EU/μg of the protein by the LAL method.
• Purity: > 90% by SDS-PAGE with silver staining
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: Mog myelin oligodendrocyte glycoprotein [ Mus musculus (house mouse) ]
• Official Symbol: Mog
• Synonyms: Mog; myelin oligodendrocyte glycoprotein; B230317G11Rik; myelin-oligodendrocyte glycoprotein
• Gene ID: 17441
• mRNA Refseq: NM_010814
• Protein Refseq: NP_034944
• UniProt ID: Q61885