Recombinant Human MOG protein(Gly30-Tyr149), His-tagged
Cat.No. : | MOG-3828H |
Product Overview : | Recombinant Human MOG (NP_996532.2) (Gly 30-Tyr 149) was expressed in E. coli, fused with a polyhistidine tag at the C-terminus and an additional Met at the N-terminus. |
Availability | July 26, 2024 |
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Source : | E. coli |
Species : | Human |
Tag : | His |
Protein length : | Gly30-Tyr149 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The secreted recombinant human MOG comprises 127 amino acids with a predicted molecular mass of 15 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions. |
Purity : | > 97 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | MOG myelin oligodendrocyte glycoprotein [ Homo sapiens ] |
Official Symbol : | MOG |
Synonyms : | MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5; MOGIG2; NRCLP7; MGC26137; |
Gene ID : | 4340 |
mRNA Refseq : | NM_001008228 |
Protein Refseq : | NP_001008229 |
MIM : | 159465 |
UniProt ID : | Q16653 |
Products Types
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MOG-063H | Recombinant Human MOG Protein, C-6×His-tagged | +Inquiry |
MOG-443C | Recombinant Cynomolgus Monkey MOG Protein, His (Fc)-Avi-tagged | +Inquiry |
Mog-6988M | Recombinant Mouse Mog protein(Gly29-Thr156), His-tagged | +Inquiry |
◆ Native Protein | ||
MOG-20 | Native Mouse/Rat MOG (35-55) Protein | +Inquiry |
◆ Lysates | ||
MOG-1126HCL | Recombinant Human MOG cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewExcellent in protein studies.
Reliable, efficient, and effective.
Worked well, great quality.
Q&As (7)
Ask a questionMOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.
MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.
MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.
There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.
MOG contributes to myelin integrity, aiding in proper nerve signal transmission.
MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.
MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.
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