Recombinant Mouse Mog Protein, His-tagged

• Cat.No.: Mog-634M
• Product Overview: Recombinant Mouse Mog(Gly29~Gly153) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: Mog played an important role in many functions.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 15.53kDa
• Identity: Reconstitute in PBS or others
• Protein length: Gly29~Gly153
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: Mog myelin oligodendrocyte glycoprotein [ Mus musculus ]
• Official Symbol: Mog
• Synonyms: MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; B230317G11Rik
• Gene ID: 17441
• mRNA Refseq: NM_010814
• Protein Refseq: NP_034944
• UniProt ID: Q61885

Reviews

11/20/2022

Excellent in protein studies.

03/14/2022

Reliable, efficient, and effective.

11/23/2021

Worked well, great quality.

Q&As

In which cells or tissues is MOG predominantly expressed?

MOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.

What role does MOG play in autoimmune demyelinating diseases?

MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.

What diagnostic or therapeutic strategies involve MOG in the context of demyelinating diseases?

MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.

Are there known genetic mutations or alterations in MOG associated with specific neurological conditions?

There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.

How does MOG contribute to the integrity and function of the myelin sheath?

MOG contributes to myelin integrity, aiding in proper nerve signal transmission.

How is MOG implicated in the pathogenesis of Multiple Sclerosis (MS)?

MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.

What is the primary function of MOG in the nervous system?

MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.