Recombinant Human MOG Protein, His/Avi-tagged, Biotinylated
Cat.No. : | MOG-02H |
Product Overview : | Recombinant biotinylated human MOG protein with His/Avi-tag was expressed in HEK293 |
Availability | July 27, 2024 |
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Description : | The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Source : | HEK293 |
Species : | Human |
Tag : | His&Avi |
Molecular Mass : | The protein has a calculated MW of 17 kDa. |
AA Sequence : | GQFRVIGPRHPIRALVGDEVELPCR ISPGKNATGMEVGWYRPPFSRVVHL YRNGKDQDGDQAPEYRGRTELLKDA IGEGKVTLRIRNVRFSDEGGFTCFF RDHSYQEEAAMELKVEDPFYWVSPG VDHHHHHHGLNDIFEAQKIEWHE |
Endotoxin : | <1 EU/μg |
Purity : | >90% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from sterile PBS, pH7.4, 5% trehalose, 5% mannitol |
Gene Name : | MOG myelin oligodendrocyte glycoprotein [ Homo sapiens (human) ] |
Official Symbol : | MOG |
Synonyms : | MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5; MOGIG2; NRCLP7; MGC26137; |
Gene ID : | 4340 |
mRNA Refseq : | NM_001008228 |
Protein Refseq : | NP_001008229 |
MIM : | 159465 |
UniProt ID : | Q16653 |
Products Types
◆ Recombinant Protein | ||
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Mog-4111M | Recombinant Mouse Mog Protein, Myc/DDK-tagged | +Inquiry |
MOG-443C | Recombinant Cynomolgus Monkey MOG Protein, His (Fc)-Avi-tagged | +Inquiry |
MOG-3828H | Recombinant Human MOG protein(Gly30-Tyr149), His-tagged | +Inquiry |
◆ Native Protein | ||
MOG-20 | Native Mouse/Rat MOG (35-55) Protein | +Inquiry |
◆ Lysates | ||
MOG-1126HCL | Recombinant Human MOG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewExcellent in protein studies.
Reliable, efficient, and effective.
Worked well, great quality.
Q&As (7)
Ask a questionMOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.
MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.
MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.
There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.
MOG contributes to myelin integrity, aiding in proper nerve signal transmission.
MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.
MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.
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