Recombinant Human MOG Protein, HIS-tagged

• Cat.No.: MOG-061H
• Product Overview: Recombinant Human MOG fused with His tag at C-termina was expressed in HEK293 cells.

Specification

• Description: The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Source: HEK293 cells
• Tag: HIS
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
• Molecular Mass: 15.31kD
• AA Sequence: GQFRVIGPRHPIRALVGDEVELPCR ISPGKNATGMEVGWYRPPFSRVVHL YRNGKDQDGDQAPEYRGRTELLKDA IGEGKVTLRIRNVRFSDEGGFTCFF RDHSYQEEAAMELKVEDPFYWVSPG VDHHHHHH
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: MOG myelin oligodendrocyte glycoprotein [ Homo sapiens ]
• Official Symbol: MOG
• Synonyms: MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5; MOGIG2; NRCLP7; MGC26137
• Gene ID: 4340
• mRNA Refseq: NM_001008228
• Protein Refseq: NP_001008229
• MIM: 159465
• UniProt ID: Q16653