Recombinant Mouse Tslp Protein, His-tagged

• Cat.No.: Tslp-01M
• Product Overview: Recombinant Mouse TSLP (20-140 aa, 130aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using
  conventional chromatography techniques.

Specification

• Description: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. Can induce allergic inflammation by directly activating mast cells.
• Source: Insect cell
• Species: Mouse
• Tag: His
• Form: Liquid
• Molecular Mass: 15 kDa
• Protein length: 20-140
• AA Sequence: YNFSNCNFTSITKIYCNIIFHDLTG DLKGAKFEQIEDCESKPACLLKIEY YTLNPIPGCPSLPDKTFARRTREAL NDHCPGYPETERNDGTQEMAQEVQN ICLNQTSQILRLWYSFMQSPE
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by absorbance at 280nm)
• Storage Buffer: Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: Tslp thymic stromal lymphopoietin [ Mus musculus (house mouse) ]
• Official Symbol: Tslp
• Synonyms: Tslp; thymic stromal lymphopoietin; thymic stromal lymphopoietin; thymic stroma-derived lymphopoietin
• Gene ID: 53603
• mRNA Refseq: NM_021367
• Protein Refseq: NP_067342
• UniProt ID: Q9JIE6

Reviews

04/04/2019

The TSLP protein offered by the manufacturer excels in its quality and is an excellent match for my experimental requirements.

02/25/2019

Their team of experts is readily available to address any queries or concerns I may have regarding the TSLP protein.

11/22/2016

Their team of experts is readily available to address any concerns or queries I may have regarding the TSLP protein.

Q&As

Can WDR5 play a role in non-cancerous diseases?

Yes, WDR5 has been associated with neurodevelopmental disorders, suggesting a role in non-cancerous diseases as well.

How does WDR5 affect neurodevelopment?

WDR5 regulates the expression of genes critical for neural development, and dysregulation can lead to developmental disorders.

Are there any clinical trials involving WDR5-targeted therapies?

Yes, there are ongoing clinical trials to test the safety and efficacy of WDR5-targeted therapies in cancer patients.

Is there a connection between WDR5 and autoimmune diseases?

Some studies suggest a potential link between WDR5 and autoimmune diseases, but further research is needed to confirm this association.

How can WDR5 be used as a diagnostic marker for cancer?

Elevated levels of WDR5 in certain cancers can serve as a diagnostic marker when detected in patient samples.