Active GMP Recombinant Human TIGIT protein, Fc-tagged

• Cat.No.: TIGIT-434HG
• Product Overview: GMP Recombinant Human TIGIT protein(NP_776160.2)(351 aa), fused with Fc Tag at the C-terminal, was expressed in HEK293 cell in an animal component free process under cGMP guidelines.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: DNA sequence encoding Human TIGIT(NCBI Reference Sequence: NP_776160.2) was expressed with Fc tag at the C-terminal.
• Form: Freeze-dried powder contains Sterile PBS (pH 7.4) with 6% mannitol.
• Bio-activity: The concentration of immobilized Human CD155(His tag) is 10ug/mL(100uL/well), and the linear binding range that can bind to TIGIT (Fc tag) is 15-500 ng/mL.
• Molecular Mass: Recombinant Human TIGIT protein contains 351 aa. It has a predicted MW of 40 kDa.
• Endotoxin: <0.1EU/ug
• Purity: >=95% by SDS-PAGE and HPLC
• Storage: The lyophilized preparation can be stored at 4°C for 24 months, and the dissolved liquid can be stored at -20°C for 6-12 months to avoid repeated freezing and thawing
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: TIGIT T cell immunoreceptor with Ig and ITIM domains [ Homo sapiens ]
• Official Symbol: TIGIT
• Synonyms: VSIG9; VSTM3
• Gene ID: 201633
• mRNA Refseq: NM_173799
• Protein Refseq: NP_776160
• MIM: 612859
• UniProt ID: Q495A1