Active Native Human Factor H
| Cat.No. : | CFH-115H |
| Product Overview : | Complement factor H (fH) is purified from normal human serum. |
- Specification
- Gene Information
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| Description : | It is an essential regulatory component of the alternative pathway of complement. It is critical for prevention of complement activation on host cells and tissues, especially the kidney. It has two functional activities: 1) it controls the formation and decay of the alternative pathway C3/C5 convertase (decay accelerating activity) and 2) it acts as a cofactor for factor I which proteolytically inactivates C3b when C3b is bound to factor H (cofactor activity). |
| Source : | Human serum |
| Species : | Human |
| Form : | Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. |
| Bio-activity : | >90% versus normal human serum standard |
| Molecular Mass : | 155,000 Da (single chain) |
| Purity : | ≥95% by SDS-PAGE |
| Storage : | Store at -70°C or below. Avoid freeze/thaw. |
| Concentration : | 1 mg/ml |
| Gene Name : | CFH complement factor H [ Homo sapiens ] |
| Official Symbol : | CFH |
| Synonyms : | CFH; complement factor H; H factor 1 (complement) , HF, HF1, HF2; age related maculopathy susceptibility 1; ARMS1; beta 1H; FHL1; H factor 2 (complement); HUS; beta-1H; factor H; factor H-like 1; beta-1-H-globulin; H factor 1 (complement); adrenomedullin |
| Gene ID : | 3075 |
| mRNA Refseq : | NM_000186 |
| Protein Refseq : | NP_000177 |
| MIM : | 134370 |
| UniProt ID : | P08603 |
| Chromosome Location : | 1q32 |
| Pathway : | Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Regulation of Complement cascade, organism-specific biosystem; Staphylococcus aureus infection, organism-specific biosystem; |
Products Types
| ◆ Recombinant Protein | ||
| Cfh-761M | Recombinant Mouse Cfh Protein, His-tagged | +Inquiry |
| CFH-763H | Recombinant Human CFH Protein, His-tagged | +Inquiry |
| CFH-762H | Recombinant Human CFH Protein, His-tagged | +Inquiry |
| Cfh-1612M | Recombinant Mouse Cfh Protein, His (Fc)-Avi-tagged | +Inquiry |
| CFH-1168H | Recombinant Human CFH Protein, GST-Tagged | +Inquiry |
| ◆ Native Protein | ||
| CFH-23H | Active Native Human Complement factor H | +Inquiry |
| ◆ Lysates | ||
| CFH-2409HCL | Recombinant Human CFH cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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