Active Recombinant Human ACVR2A, Fc-tagged, Biotinylated
| Cat.No. : | ACVR2A-532H |
| Product Overview : | The recombinant human ACVR2A-Fc fusion protein is expressed as a 344 amino acid protein consisting of Ala20 - Pro135 region of ACVR2A (UniProt accession #P27037) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition. |
- Specification
- Gene Information
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| Source : | Human cells |
| Species : | Human |
| Tag : | Fc |
| Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
| Bio-activity : | Immobilized ACVR2A binds Activin or Inhibin in a functional ELISA. Neutralize Activin-induced inhibition of MPC11 cell proliferation and hemoglobin expression in K562 human chronic myelogenous leukemia cells. |
| Molecular Mass : | Calculated molecular mass (kDa): 39.0; Estimated by SDS-PAGE under reducing condition (kDa): ~55 |
| AA Sequence : | AILGRSETQECLFFNANWEKDRTNQ TGVEPCYGDKDKRRHCFATWKNISG SIEIVKQGCWLDDINCYDRTDCVE KKDSPEVYFCCCEGNMCNEKFSYFP EMEVTQPTSNPVTPKPPSTGTHTCP PCPAPELLGGPSVFLFPPKPKDTL MISRTPEVTCVVVDVSHEDPEVKFN WYVDGVEVHNAKTKPREEQYNSTYR VVSVLTVLHQDWLNGKEYKCKVS NKALPAPIEKTISKAKGQPREPQVY TLPPSREEMTKNQVSLTCLVKGFYP SDIAVEWESNGQPENNYKTTPPVL DSDGSFFLYSKLTVDKSRWQQGNVF SCSVMHEALHNHYTQKSLSLSPGK |
| Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the |
| Purity : | >95% judged by SDS-PAGE under reducing condition. |
| Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
| Gene Name : | ACVR2A activin A receptor, type IIA [ Homo sapiens ] |
| Official Symbol : | ACVR2A |
| Synonyms : | ACVR2A; activin A receptor, type IIA; activin A receptor, type II , ACVR2; activin receptor type-2A; ACTRII; ACVR2; |
| Gene ID : | 92 |
| mRNA Refseq : | NM_001616 |
| Protein Refseq : | NP_001607 |
| MIM : | 102581 |
| UniProt ID : | P27037 |
| Chromosome Location : | 2q22.2-q23.3 |
| Pathway : | ALK1 signaling events, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by BMP, organism-specific biosystem; |
| Function : | ATP binding; contributes_to activin binding; activin receptor activity, type II; contributes_to activin-activated receptor activity; coreceptor activity; growth factor binding; inhibin beta-A binding; inhibin beta-B binding; metal ion binding; nucleotide binding; protein binding; contributes_to protein binding; protein self-association; protein serine/threonine kinase activity; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; |
Products Types
| ◆ Recombinant Protein | ||
| ACVR2A-26487TH | Recombinant Human ACVR2A | +Inquiry |
| ACVR2A-01H | Recombinant Active Human ACVR2A Protein, His-tagged | +Inquiry |
| Acvr2a-01M | Active Recombinant Mouse Acvr2a Protein, mFc tagged | +Inquiry |
| ACVR2A-150R | Recombinant Rat ACVR2A Protein, His (Fc)-Avi-tagged | +Inquiry |
| ACVR2A-0786H | Recombinant Human ACVR2A Protein (P191-N487), His tagged | +Inquiry |
| ◆ Lysates | ||
| ACVR2A-3096HCL | Recombinant Human ACVR2A cell lysate | +Inquiry |
| ACVR2A-2280MCL | Recombinant Mouse ACVR2A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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