Active Recombinant Human BRD4 (BD1) Protein (49-170), N-His tagged
Cat.No. : | BRD4-35H |
Product Overview : | Active Recombinant human BRD4 (BD1) (49-170) was expressed in E. coli cells using an N-terminal His tag. |
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Description : | Bromodomain-containing protein 4 (BRD4) is a member of the bromodomain and extra-terminal domain (BET) protein family. BRD4 contains two tandem bromodomains: BD1 and BD2. BRD4 (BD1) functions as an epigenetic reader – recognizing and interpreting histone acetylation marks to recruit transcriptional machinery and chromatin remodeling complexes. BRD4 (BD1) is involved in the regulation of cell cycle progression, with its overexpression promoting cell proliferation and survival. Furthermore, it has been implicated in the development and progression of cancer as it regulates the expression of oncogenes and tumor suppressor genes. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Bio-activity : | 2,908 ng/min/mg |
Molecular Mass : | Observed MW: ~15 kDa Calculated MW: ~14.7 kDa |
Protein length : | 49-170 |
Purity : | > 90% |
Stability : | One year at –70 centigrade from date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μL |
Storage Buffer : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.25mM DTT, 25% glycerol. |
Shipping : | Dry ice |
Gene Name : | BRD4 bromodomain containing 4 [ Homo sapiens (human) ] |
Official Symbol : | BRD4 |
Synonyms : | BRD4; bromodomain containing 4; bromodomain-containing protein 4; CAP; chromosome associated protein; HUNK1; HUNKI; MCAP; bromodomain-containing 4; chromosome-associated protein; |
Gene ID : | 23476 |
mRNA Refseq : | NM_014299 |
Protein Refseq : | NP_055114 |
MIM : | 608749 |
UniProt ID : | O60885 |
Products Types
◆ Recombinant Protein | ||
BRD4-05H | Recombinant Human BRD4 Protein (44-460), N-His tagged | +Inquiry |
BRD4-38H | Active Recombinant Human BRD4 (BD2) Protein (342-460), N-His tagged | +Inquiry |
BRD4-0297H | Recombinant Human BRD4 Protein (S42-E168), Tag Free | +Inquiry |
BRD4-4831H | Recombinant Human BRD4 protein, His&FLAG-tagged | +Inquiry |
BRD4-4832H | Recombinant Human BRD4 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
BRD4-179HCL | Recombinant Human BRD4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1696 | BRD4 (BD1) Inhibitor Screening Assay Kit | +Inquiry |
Kit-1697 | BRD4 (BD1) TR-FRET Assay Kit | +Inquiry |
Kit-1699 | BRD4 (BD2) Inhibitor Screening Assay Kit | +Inquiry |
Kit-1698 | BRD4 (BD1+BD2) TR-FRET Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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