Active Recombinant Human CCL16 Protein (97 aa)
Cat.No. : | CCL16-268C |
Product Overview : | Recombinant human HCC-4/CCL16 produced in CHO cells is a single non-glycosylated polypeptide chain containing 97 amino acids. A fully biologically active molecule, rhHCC-4/CCL16has a molecular mass of 12 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Description : | Human HCC4, also named NCC4and Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). It can signal through the CCR8 and CCR1 receptors, and it is chemotactic towards monocytes and lymphocytes but not neutrophils. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly up-regulated in the presence of IL-10. HCC-4 induces a calcium flux in thp-1 cells that are desensitized prior to the expression of RANTES. |
Source : | CHO |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | The EC50 value of human HCC-4/CCL16 on Ca^2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 1.5 μg/mL. |
Molecular Mass : | 12 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 97 |
AA Sequence : | QPKVPEWVNTPSTCCLKYYEKVLPR RLVVGYRKALNCHLPAIIFVTKRNR EVCTNPNDDWVQEYIKDPNLPLLPT RNLSTVKIITAKNGQPQLLNSQ |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 98% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant human HCC-4/CCL16 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, human HCC-4/CCL16 should be stable up to 1 week at 4 centigrade or up to 2 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/mL. |
Gene Name : | CCL16 chemokine (C-C motif) ligand 16 [ Homo sapiens ] |
Official Symbol : | CCL16 |
Synonyms : | CCL16; chemokine (C-C motif) ligand 16; SCYA16, small inducible cytokine subfamily A (Cys Cys), member 16; C-C motif chemokine 16; CKb12; HCC 4; LCC 1; LEC; LMC; Mtn 1; NCC 4; SCYL4; monotactin-1; chemokine LEC; chemokine CC-4; new CC chemokine 4; liver CC chemokine-1; IL-10-inducible chemokine; liver-expressed chemokine; small-inducible cytokine A16; lymphocyte and monocyte chemoattractant; small inducible cytokine subfamily A (Cys-Cys), member 16; NCC4; HCC-4; LCC-1; Mtn-1; NCC-4; ILINCK; SCYA16; MGC117051; |
Gene ID : | 6360 |
mRNA Refseq : | NM_004590 |
Protein Refseq : | NP_004581 |
MIM : | 601394 |
UniProt ID : | O15467 |
Products Types
◆ Recombinant Protein | ||
CCL16-113C | Active Recombinant Human CCL16 Protein (97 aa) | +Inquiry |
CCL16-0613H | Recombinant Human CCL16 Protein, GST-Tagged | +Inquiry |
CCL16-1014H | Recombinant Human CCL16 Protein (Gln24-Gln120), N-GST tagged | +Inquiry |
CCL16-353H | Active Recombinant Human CCL16, MIgG2a Fc-tagged | +Inquiry |
CCL16-29941TH | Recombinant Human CCL16 | +Inquiry |
◆ Lysates | ||
CCL16-7730HCL | Recombinant Human CCL16 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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