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Active Recombinant Human / Cynomolgus / Rhesus macaque ROR1 protein, mFc-tagged

Cat.No. : ROR1-0656H
Product Overview : Recombinant Human / Cynomolgus / Rhesus macaque ROR1 protein(Gln30-Glu403), fused with mFc tag, was expressed in HEK293.
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Source : HEK293
Species : Human / Cynomolgus / Rhesus macaque
Tag : mFc
Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Bio-activity : Immobilized Human / Cynomolgus / Rhesus macaque ROR1, Mouse IgG2a Fc Tag at 1 μg/mL (100 μL/well) can bind Anti-ROR1 Antibody,Human IgG1 | Kappa with a linear range of 0.08-3 ng/mL.
Molecular Mass : This protein carries a mouse IgG2a Fc tag at the C-terminus.The protein has a calculated MW of 68.9 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Proteinlength : Gln30-Glu403
Endotoxin : Less than 0.1 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : ROR1 receptor tyrosine kinase-like orphan receptor 1 [ Homo sapiens ]
Official Symbol : ROR1
Synonyms : ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase receptor-related 1; neurotrophic tyrosine kinase, receptor-related 1; dJ537F10.1; MGC99659;
Gene ID : 4919
mRNA Refseq : NM_001083592
Protein Refseq : NP_001077061
MIM : 602336
UniProt ID : Q01973

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (4)

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What is the expression level of ROR1 in normal tissues. 11/28/2022

ROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.

What are the effects of inhibiting ROR1 expression? 07/14/2022

Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.

What biological processes is ROR1 involved in? 12/26/2021

ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.

What diseases is ROR1 involved in? 03/01/2021

ROR1 is involved in the study of breast, lung and ovarian cancers.

Customer Reviews (3)

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Reviews
10/18/2022

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    08/13/2022

      Excellent after-sales service, solving many experimental problems.

      04/12/2021

        Fast and timely shipment helped me to get satisfactory experimental results in short time.

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