Active Recombinant Human IGF1 Protein, Tag Free, GMP Grade

• Cat.No.: IGF1-03H
• Product Overview: Recombinant Human IGF1 Protein without tag was expressed in Yeast

Specification

• Species: Human
• Source: Yeast
• Tag: Non
• Description: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
• Form: White or off-white lyophilized powder
• Bio-activity: ≥2×10^5 IU /mg pro. The biological activity is determined by assessing the stimulatory effect of IGF-1 on the human breast cancer cell line MCF-7.
• Molecular Mass: 7.7 kDa ± 0.8 kDa
• Endotoxin: < 0.2 EU/μg
• Purity: ≥98%(SDS-PAGE)
• Storage: Store at -15 to -20 centigrade, stable for up to 24 months.
• Reconstitution: It is recommended to briefly centrifuge the tube before opening to settle the powder at the bottom. Then, dissolve the powder in sterilized deionized water to prepare a 100 μg/mL stock solution, which can be stored stably at 2-8 centigrade for one week. When diluting to lower concentrations (not below 10 μg/mL), 0.1% BSA or HSA must be added. To extend storage time, freezing at -70 or -20 centigrade is recommended. Repeated freezing and thawing should be avoided.

Gene Information

• Gene Name: IGF1 insulin like growth factor 1 [ Homo sapiens (human) ]
• Official Symbol: IGF1
• Synonyms: IGF1; insulin like growth factor 1; IGF; MGF; IGFI; IGF-I; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor IB; mechano growth factor; somatomedin-C
• Gene ID: 3479
• mRNA Refseq: NM_000618
• Protein Refseq: NP_000609
• MIM: 147440
• UniProt ID: Q59GC5