Active Recombinant Human IL22RA1 protein, hFc-tagged
|Product Overview :||Recombinant Human IL22RA1 protein(Q8N6P7)(His16-Thr228) is expressed from Expi293 with hFc tag at the C-terminal.|
- Gene Information
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|Form :||Supplied as 0.22μm filtered solution in PBS (pH 7.4). Please dilute to the desired concentration according to the concentration of the solution shown on the product label.|
|Bio-activity :||Immobilized Human IL-22, His Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 10.2ng/ml determined by ELISA.|
|Molecular Mass :||The protein has a predicted MW of 51 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result.|
|Protein length :||His16-Thr228|
|Endotoxin :||Less than 1.0 EU per μg by the LAL method.|
|Purity :||> 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC
|Storage :||Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please do not repeated freeze-thaw cycles.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.|
|Gene Name :||IL22RA1 interleukin 22 receptor, alpha 1 [ Homo sapiens ]|
|Official Symbol :||IL22RA1|
|Synonyms :||IL22RA1; interleukin 22 receptor, alpha 1; IL22R, interleukin 22 receptor; interleukin-22 receptor subunit alpha-1; CRF2 9; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22R; CRF2-9; IL22R1|
|Gene ID :||58985|
|mRNA Refseq :||NM_021258|
|Protein Refseq :||NP_067081|
|UniProt ID :||Q8N6P7|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
IL22RA1 undergoes phosphorylation.
IL22RA1 enhances IL22 signaling by forming a complex with IL-10R2.
IL22RA1 polymorphisms affect disease susceptibility in Crohn's disease.
IL22RA1 is involved in anti-tumor immunity by activating STAT3.
IL22RA1 expression is upregulated in autoimmune diseases like psoriasis.
IL22RA1 enhances epithelial barrier function.
IL22RA1 expression is tissue-specific, being high in the liver and skin.
IL22RA1 interacts with IL-10R2 and IL-20RB.
IL22 has high affinity for IL22RA1.
IL22RA1 has multiple alternative splicing variants.
Customer Reviews (3)Write a review
High stability in serum. -
Suitable for receptor binding. -
Effective in autoimmune studies. -
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