Recombinant Rat Il22ra1 protein, His-tagged

• Cat.No.: Il22ra1-1116R
• Product Overview: Recombinant Rat Il22ra1 protein(NP_001178798.1)(Met1-Ala228), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Rat
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant rat Il22ra1 consists 222 amino acids and predicts a molecular mass of 25.5 kDa.
• Protein length: Met1-Ala228
• Endotoxin: < 1.0 EU per μg protein as determined by the LAL method.
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Il22ra1 interleukin 22 receptor, alpha 1 [ Rattus norvegicus ]
• Official Symbol: Il22ra1
• Synonyms: IL22RA1; interleukin 22 receptor, alpha 1; interleukin-22 receptor subunit alpha-1; RGD1559655
• Gene ID: 362629
• mRNA Refseq: NM_001191869
• Protein Refseq: NP_001178798

Reviews

12/18/2022

High stability in serum.

09/04/2017

Suitable for receptor binding.

10/16/2016

Effective in autoimmune studies.

Q&As

What post-translational modifications occur on IL22RA1?

IL22RA1 undergoes phosphorylation.

How does IL22RA1 contribute to IL22 signaling?

IL22RA1 enhances IL22 signaling by forming a complex with IL-10R2.

What impact do IL22RA1 polymorphisms have on disease susceptibility?

IL22RA1 polymorphisms affect disease susceptibility in Crohn's disease.

Is IL22RA1 involved in anti-tumor immunity?

IL22RA1 is involved in anti-tumor immunity by activating STAT3.

How does IL22RA1 expression change in autoimmune diseases?

IL22RA1 expression is upregulated in autoimmune diseases like psoriasis.

How does IL22RA1 contribute to epithelial barrier function?

IL22RA1 enhances epithelial barrier function.

Is IL22RA1 expression tissue-specific?

IL22RA1 expression is tissue-specific, being high in the liver and skin.

Does IL22RA1 interact with other receptors?

IL22RA1 interacts with IL-10R2 and IL-20RB.

What is the affinity of IL22 for IL22RA1?

IL22 has high affinity for IL22RA1.

Does IL22RA1 have alternative splicing variants?

IL22RA1 has multiple alternative splicing variants.