Recombinant Human IL22RA1 protein, His-SUMO-tagged

Cat.No. : IL22RA1-4649H
Product Overview : Recombinant Human IL22RA1 protein(Q8N6P7)(250-573aa), fused to N-terminal His-SUMO tag, was expressed in E. coli
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Source : E. coli
Species : Human
Tag : His-SUMO
Form : If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Molecular Mass : 50.8 kDa
Protein length : 250-573aa
Purity : Greater than 90% as determined by SDS-PAGE.
Storage : Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Reconstitution : Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.
Gene Name : IL22RA1 interleukin 22 receptor, alpha 1 [ Homo sapiens ]
Official Symbol : IL22RA1
Synonyms : IL22RA1; interleukin 22 receptor, alpha 1; IL22R, interleukin 22 receptor; interleukin-22 receptor subunit alpha-1; CRF2 9; IL-22RA1; zcytoR11; IL-22R-alpha-1; IL-22 receptor subunit alpha-1; cytokine receptor class-II member 9; cytokine receptor family 2 member 9; IL22R; CRF2-9; IL22R1;
Gene ID : 58985
mRNA Refseq : NM_021258
Protein Refseq : NP_067081
MIM : 605457
UniProt ID : Q8N6P7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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What post-translational modifications occur on IL22RA1? 11/18/2022

IL22RA1 undergoes phosphorylation.

How does IL22RA1 contribute to IL22 signaling? 03/01/2022

IL22RA1 enhances IL22 signaling by forming a complex with IL-10R2.

What impact do IL22RA1 polymorphisms have on disease susceptibility? 08/13/2021

IL22RA1 polymorphisms affect disease susceptibility in Crohn's disease.

Is IL22RA1 involved in anti-tumor immunity? 07/01/2021

IL22RA1 is involved in anti-tumor immunity by activating STAT3.

How does IL22RA1 expression change in autoimmune diseases? 05/25/2021

IL22RA1 expression is upregulated in autoimmune diseases like psoriasis.

How does IL22RA1 contribute to epithelial barrier function? 04/28/2021

IL22RA1 enhances epithelial barrier function.

Is IL22RA1 expression tissue-specific? 05/21/2020

IL22RA1 expression is tissue-specific, being high in the liver and skin.

Does IL22RA1 interact with other receptors? 01/20/2020

IL22RA1 interacts with IL-10R2 and IL-20RB.

What is the affinity of IL22 for IL22RA1? 02/13/2016

IL22 has high affinity for IL22RA1.

Does IL22RA1 have alternative splicing variants? 01/05/2016

IL22RA1 has multiple alternative splicing variants.

Customer Reviews (3)

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Reviews
12/18/2022

    High stability in serum.

    09/04/2017

      Suitable for receptor binding.

      10/16/2016

        Effective in autoimmune studies.

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