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Active Recombinant Human MAP3K14, GST-tagged
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Cat.No. : | MAP3K14-1065H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human NIK (325-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description : | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
Source : | Sf9 insect cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 8 nmol/min/mg |
Molecular Mass : | ~108 kDa |
Protein length : | 325-end |
Purity : | >85% |
Applications : | Kinase Assay; Western Blot |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name : | MAP3K14 mitogen-activated protein kinase kinase kinase 14 [ Homo sapiens ] |
Official Symbol : | MAP3K14 |
Synonyms : | mitogen-activated protein kinase kinase kinase 14; HS; NIK; HSNIK; FTDCR1B; MAP3K14; NF-kappa-beta-inducing kinase; serine/threonine protein-kinase; serine/threonine-protein kinase NIK; EC 2.7.11.25; Serine/threonine-protein kinase NIK |
Gene ID : | 9020 |
mRNA Refseq : | NM_003954 |
Protein Refseq : | NP_003945 |
MIM : | 604655 |
UniProt ID : | Q99558 |
Chromosome Location : | 17q21 |
Pathway : | Apoptosis; Epithelial cell signaling in Helicobacter pylori infection; Intestinal immune network for IgA production; MAPK signaling pathway; T cell receptor signaling pathway |
Function : | MAP kinase kinase kinase activity; ATP binding; protein binding; protein kinase activity |
◆ Recombinant Protein
MAP3K14-2488R | Recombinant Rhesus Macaque MAP3K14 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP3K14-0626H | Recombinant Human MAP3K14 Protein (L318-P947), Tag Free | +Inquiry |
MAP3K14-894H | Recombinant Human MAP3K14 Protein, His/GST-tagged | +Inquiry |
MAP3K14-0627H | Recombinant Human MAP3K14 Protein (L318-P947), His/Strep tagged | +Inquiry |
MAP3K14-01H | Recombinant Human MAP3K14 Protein, GST&His-tagged | +Inquiry |
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◆ Lysates
MAP3K14-4507HCL | Recombinant Human MAP3K14 293 Cell Lysate | +Inquiry |
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MAP1LC3AMAP1LC3BMAP1LC3B2Map2k1MAP2K2MAP2K3MAP2K6Map3k1MAP3K14MAP3K2MAP3K3MAP3K5MAP3K8MAP4K5MAP2K4MAP3K6MAP2K5MAP2K7MAP3K11MAP4K4MAP4K2MAP4K1MAP1SMap2MAP3K13MAP3K15MAP3K4MAP3K7MAP3K7IP1MAP4MAP3K10MAP3K9MAP1AMAP1BMAP7MAP4K3MAP3K12MAP1LC3CMAP6D1MAP7D1MAP9MAP6MAP2K1IP1MAP7D2MAP7D3
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