Active Recombinant Human MAP3K14, GST-tagged
Cat.No. : | MAP3K14-1065H |
Product Overview : | Recombinant human NIK (325-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
Source : | Sf9 insect cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 8 nmol/min/mg |
Molecular Mass : | ~108 kDa |
Protein length : | 325-end |
Purity : | >85% |
Applications : | Kinase Assay; Western Blot |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name : | MAP3K14 mitogen-activated protein kinase kinase kinase 14 [ Homo sapiens ] |
Official Symbol : | MAP3K14 |
Synonyms : | mitogen-activated protein kinase kinase kinase 14; HS; NIK; HSNIK; FTDCR1B; MAP3K14; NF-kappa-beta-inducing kinase; serine/threonine protein-kinase; serine/threonine-protein kinase NIK; EC 2.7.11.25; Serine/threonine-protein kinase NIK |
Gene ID : | 9020 |
mRNA Refseq : | NM_003954 |
Protein Refseq : | NP_003945 |
MIM : | 604655 |
UniProt ID : | Q99558 |
Chromosome Location : | 17q21 |
Pathway : | Apoptosis; Epithelial cell signaling in Helicobacter pylori infection; Intestinal immune network for IgA production; MAPK signaling pathway; T cell receptor signaling pathway |
Function : | MAP kinase kinase kinase activity; ATP binding; protein binding; protein kinase activity |
Products Types
◆ Recombinant Protein | ||
MAP3K14-894H | Active Recombinant Human MAP3K14 Protein, His/GST-tagged | +Inquiry |
MAP3K14-01H | Active Recombinant Human MAP3K14 Protein, GST&His-tagged | +Inquiry |
MAP3K14-2488R | Recombinant Rhesus Macaque MAP3K14 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP3K14-0626H | Recombinant Human MAP3K14 Protein (L318-P947), Tag Free | +Inquiry |
MAP3K14-0627H | Recombinant Human MAP3K14 Protein (L318-P947), His/Strep tagged | +Inquiry |
◆ Lysates | ||
MAP3K14-4507HCL | Recombinant Human MAP3K14 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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