||Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR).
||No biological activity data is available at this time.
|Molecular Mass :
||Dimer (Noncovalently linked), 13.8/27.5 kDa (120/240 aa)
|AA Sequence :
||MYAEHKSHRGEYSVCDSESLWVTDK SSAIDIRGHQVTVLGEIKTGNSPVK QYFYETRCKEARPVKNGCRGIDDKH WNSQCKTSQTYVRALTSENNKLVGW RWIRIDTSCVCALSRKIGRT
||≤1 EUs/μg, Kinetic LAL
||≥95%, Reducing and Non-Reducing SDS PAGE
||12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
1 month when stored at 4 centigrade after reconstituting as directed.
3 months when stored at -20 to -80 centigrade after reconstituting as directed.
||Storage Prior to Reconstitution: -20 centigrade
|Storage Buffer :
||Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
||Sterile water at 0.1 mg/mL
||Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.