Active Recombinant Human PDE1C, GST-tagged
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Cat.No. : | PDE1C-1612H Optional Service: Optional requirements on this protein |
Product Overview : | Full-length recombinant human PDE1C was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description : | Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex. |
Source : | Sf9 insect cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 445 nmol/min/mg |
Molecular Mass : | ~99 kDa |
Protein length : | Full Length |
Purity : | >90% |
Applications : | PDE Assay |
Stability : | 1 yr at -70oC from date of shipment. |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Gene Name : | PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa [ Homo sapiens ] |
Official Symbol : | PDE1C |
Synonyms : | PDE1C; phosphodiesterase 1C, calmodulin-dependent 70kDa; phosphodiesterase 1C, calmodulin dependent (70kD); calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C; Hcam3; hCam-3; cam-PDE 1C; Human 3,5 cyclic nucleotide phosphodiesterase (HSPDE1C1A) |
Gene ID : | 5137 |
mRNA Refseq : | NM_005020 |
Protein Refseq : | NP_005011 |
MIM : | 602987 |
UniProt ID : | Q14123 |
Chromosome Location : | 7p14.3 |
Pathway : | Ca-dependent events; Calmodulin induced events; DAP12 interactions |
Function : | calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; metal ion binding |
◆ Recombinant Protein
PDE1C-047H | Recombinant Human PDE1C Protein, His/GST-tagged | +Inquiry |
PDE1C-03H | Recombinant Human PDE1C Protein, His/GST-tagged | +Inquiry |
Pde1c-443M | Recombinant Mouse Phosphodiesterase 1C, GST-tagged | +Inquiry |
Pde1c-4463R | Recombinant Rat Pde1c protein, His-tagged | +Inquiry |
PDE1C-4327R | Recombinant Rat PDE1C Protein | +Inquiry |
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◆ Lysates
PDE1C-001HCL | Recombinant Human PDE1C cell lysate | +Inquiry |
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◆ Assay kits
Kit-1828 | PDE1C Assay Kit I | +Inquiry |
Kit-1829 | PDE1C Assay Kit II | +Inquiry |
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Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
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