Recombinant Human PDE1C Protein, His-tagged PDE1C-146H

Recombinant Human PDE1C Protein, His-tagged

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Cat.No. : PDE1C-146H Optional Service: Optional requirements on this protein
Product Overview : Recombinant Human PDE1C, transcript variant 4, fused with His tag at N-terminal was expressed in E. coli.
Description : This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Source : E. coli
Species : Human
Tag : His
Form : 50mM Tris, 8M Urea, pH8.0.
Molecular Mass : 72 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa [ Homo sapiens ]
Official Symbol : PDE1C
Synonyms : PDE1C; phosphodiesterase 1C, calmodulin-dependent 70kDa; phosphodiesterase 1C, calmodulin dependent (70kD); calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C; Hcam3; hCam-3; cam-PDE 1C; Human 3,5 cyclic nucleotide phosphodiesterase (HSPDE1C1A);
Gene ID : 5137
mRNA Refseq : NM_001191056
Protein Refseq : NP_005011
MIM : 602987
UniProt ID : Q14123
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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