| Cat.No. : |
PDE1C-146H
Optional Service: Optional requirements on this protein
|
| Product Overview : |
Recombinant Human PDE1C, transcript variant 4, fused with His tag at N-terminal was expressed in E. coli. |
| Description : |
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His |
| Form : |
50mM Tris, 8M Urea, pH8.0. |
| Molecular Mass : |
72 kDa |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
>50 ug/mL as determined by microplate BCA method |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
